The FBI is offering $10,000 for help finding the gun of a Border Patrol agent who was slain last week in a rugged area outside San Diego.

DC Universe Online is an MMO set in the world of DC Comics. Anyone can play alongside iconic heroes like Batman and Superman or fiendish villains like Joker and Lex Luthor.

We may think of San Diego County's beaches as five-star attractions. But an environmental group says the water quality at many of our beaches get lower ratings. Part of the problem is the lack of testing.

Advocates for HIV treatment and prevention say Governor Schwarzenegger has effectively dismantled California's efforts to battle the disease. When he signed the new budget, the governor used his line-item veto power to cut an additional $52 million from HIV/AIDS programs.

The San Diego Zoo's 17-year-old giant panda Bai Yun is pregnant, it was announced today. The mother of four was subjected to an ultrasound examination on Monday that clearly showed a panda fetus, which was seen moving its paws and tucking in its head, according to the San Diego Zoo.

The low crime rate is good news for people living in San Diego. But it’s bad news when the San Diego Police Department tries to get money from the federal government.

Congress reported progress on legislation to overhaul the nation's health care Wednesday as President Barack Obama introduced a retooled message asserting his plan would protect Americans and limit insurers' power.

A new analysis of military spending in San Diego suggests defense dollars account for a growing share of the local economy.

Trash collection in San Diego has a messy history. The City Council waded into the issue Tuesday when it was forced to respond to the County Grand Jury’s report calling for San Diego to start charging for garbage pick up. It’s an issue that’s vexed local lawmakers for years.

If California is ungovernable, what can we do about it? Overhaul the constitution or tweak it here and there through the initiative process? Common Cause and the League of Women Voters are examining the alternatives, and we talk with Thad Kousser about possibilities.

Nearly 20 percent of the human genome is patented by private companies, amounting to thousands of genes. But should what exists in nature be patenting, and what impact will that have on cures for disease?

A group of activists from Oakland have filed a ballot initiative that could legalize marijuana in California.

U.S Federal officials say are arresting more U.S. Teenagers trying to smuggle drugs across the U.S.-Mexico border.

The San Diego Unified school board is leaning toward approving a proposed policy that would allow all students in the district access to full-spectrum biliteracy programs.