Genes that cause cancer to grow or an immune system to turn itself on will now be studied at a unique center in San Diego.

California’s high school dropout rate stands at just over 18 percent – with roughly three out of every four students graduating on time.

In the early 60s, clubs like the Village Vanguard were scattered throughout Greenwich Village. Now it stands alone, the last of its kind. In September 2009, a select group of fans and friends had the rare opportunity to experience the legendary Barbra Streisand’s performance in the ultimate up-close-and-personal setting of this historic club. Accompanied by piano, bass, guitar and drums, this is the artist at her most intimate.

Small business and union officials in San Diego are blasting Amazon.com's fight to keep from collecting California sales taxes.

If you drive by San Diego State University today, you'll notice a major landmark missing -- Aztec Center.

The San Diego based Legend3D contributed 2D to 3D conversion for "The Smurfs," which did surprisingly well last month at the summer box office. KPBS film critic Beth Accomando considers how the new 3D entries -- "Final Destination 5" and "Glee the 3D Concert Movie" (both opening August 12 throughout San Diego) might fare this weekend.

Officer Henwood served with the police department’s mid-city division. It includes the neighborhood of City Heights, where Henwood was gunned down last weekend.

Directed and produced by four-time Emmy Award winner Jim Brown, "Legends Of Folk: The Village Scene" celebrates the folk movement in Greenwich Village in the 1960s, featuring rare and stunning performances by Bob Dylan, Peter, Paul & Mary, Joan Baez, Judy Collins, Richie Havens, The Lovin’ Spoonful, The Mamas and the Papas, Don McLean, Neil Diamond, and more, along with contemporary interviews and segments.

An unmanned hypersonic glider developed for U.S. defense research into super-fast global strike capability was launched atop a rocket early Thursday but contact was lost after the experimental craft began flying on its own, the Defense Advanced Research Projects Agency said.

The class of 2010 at San Diego County high schools had a 15.9 percent dropout rate, below the statewide figure of 18.2 percent.

Schools across the Southwest are opening this month with smaller budgets and fewer resources, forcing districts to come up with creative ways to make up for huge monetary losses.

Nearly a decade ago the state flagged thousands of schools for possible earthquake risks -- why have many gone unchecked?

A grunion run, a Rocky Horror flash mob, beer and chocolate. It's another eclectic mix of options for your San Diego weekend.

For the first time since the advent of his spectacular international popularity, superstar Andrea Bocelli returns to his native Italy for a concert of his greatest hits along with the debut of some new songs. Taped at the glorious Teatro di Silenzio, nestled in the beautiful, rolling countryside near the ancient Tuscan village of Volterra, Bocelli is joined by special guests trumpeter Chris Botti, Heather Headley, Kenny G., David Foster, Lang Lang, and Sarah Brightman for an evening of romantic favorites.

According to theoretical physicist Dr. Geoffrey West, cities of similar size are alike in many ways. He says that population numbers can predict details about a city, from crime rate to economic activity.

The American troops killed in the deadliest single mission of the Afghan war came from two dozen states and all corners of the nation, mostly young men in their 20s and 30s.

"3 Steps To Incredible Health! With Joel Fuhrman, M.D." directly addresses the crisis of obesity and chronic disease plaguing America. Over 65% of Americans are overweight or obese — and that number is growing just like our waistlines. Dr. Fuhrman’s revolutionary health plan is not about will power, but instead offers knowledge and a healthy, effective, and scientifically proven plan for shedding weight quickly and reclaiming the vitality and good health we all deserve.

While Wall Street experiences the biggest stock sell-off in years, some very successful investors don't appear to be concerned. They're out buying stocks while everybody else panics.

Two Miramar-based Marines who were aboard a Marine Corps F/A-18 Hornet fighter jet that crashed in the Pacific Ocean off Mexico were rescued early today, a Coast Guard spokesman said.

Children go to school in roughly 200 buildings across San Diego County where earthquake safety is still an unanswered question.