Open enrollment in Medicare opened this weekend, making it a stressful time of year for many San Diego seniors.

A San Diego company has developed a non-invasive test to detect Down syndrome in unborn babies.

It’s Monday, and that means Home Post has another Prince Harry sighting to report. This time British Army Capt. Harry Wales was spotted at Solana Beach music venue “Belly Up.”

Jerry Lee, chancellor of the National University System since 2001, will step down at the end of the next calendar year, the school announced today.

A proposal to raise the cost of parking lot events at Qualcomm Stadium and parking for attendees was approved today by the San Diego City Council.

The San Diego City Council waded into water issues today: The council approved a policy aimed at securing the city’s water supply.

Scientists are on the verge of answering one of the greatest questions in history: Are we alone? Combining the latest telescope images with dazzling CGI, "Finding Life Beyond Earth" immerses audiences in the sights and sounds of alien worlds, while top astrobiologists explain how these places are changing how we think about the potential for life in our solar system.

The historic nuclear accident at Chernobyl is now 25 years old. Filmmakers and scientists set out to document the lives of the packs of wolves and other wildlife thriving in the “dead zone” that still surrounds the remains of the reactor. As the top predators in this new wilderness, wolves best reflect the condition of the entire ecosystem because if the wolves are doing well, the populations of their prey must also be doing well. Accordingly, a key long-term study of the wolves has been initiated to determine their health, their range, and their numbers.

Many older people are finding it particularly difficult to get hired. Some say age discrimination is a key factor working against them.

More than 100 of downtown San Diego's most vulnerable homeless identified in a survey last year have been provided with housing, and homeless advocates said today they are preparing to give the same assistance to another 125.

City Heights is transforming from a sleepy San Diego suburb to a vibrant and diverse community of immigrants and refugees. It is among San Diego's poorest neighborhoods and its challenges have attracted millions of dollars' worth of private and public investments. This makes City Heights a microcosm of change that could inform other diversifying and growing neighborhoods. In a three-part series this week starting Tuesday, we show how longtime residents can learn how to eat better from City Heights refugees.

This episode tells the story of the Liberian women who took on the warlords and regime of dictator Charles Taylor in the midst of a brutal civil war, and won a once unimaginable peace for their shattered country in 2003. As the rebel noose tightened around the capital city of Monrovia, thousands of women -- ordinary mothers, grandmothers, aunts and daughters, both Christian and Muslim -- formed a thin but unshakable line between the opposing forces. Armed only with white t-shirts and the courage of their convictions, they literally faced down the killers who had turned Liberia into hell on earth.

A magnitude-3.1 earthquake was recorded 46 miles east- southeast of San Diego today, according to the U.S. Geological Survey.

Down Syndrome: An indepth look at what families are doing, resources available and clinical trials underway here in San Diego.

San Diego tea party and Occupy San Diego -- what do they have in common?

Scott Peters, the port commissioner and former San Diego councilman, announced today that he will run for Congress and challenge incumbent Republican Brian Bilbray.

Last year, the Obama administration set new records for detaining and deporting immigrants who were inside the country illegally. The government plans to best those numbers in 2011, removing more than 400,000 people. In partnership with American University’s Investigative Reporting Workshop, FRONTLINE correspondent Maria Hinojosa takes a penetrating look at Obama’s vastly expanded immigration net, explores the controversial Secure Communities enforcement program and goes inside the hidden world of immigration detention in "Lost In Detention."

Some alternative newspapers get a large percentage of their advertising revenue from medical marijuana dispensaries. Now that U.S. attorneys in California are cracking down on these establishments, the weekly publications could feel the pain.

The Sweetwater Union High School District board was scheduled to meet today to discuss banning students from using synthetic drugs that are disguised as incense but mimic the highs of cocaine and marijuana when smoked.

Mexico ships televisions, cars, sugar and medical equipment to the United States. Soon, it may be sending water north.

Engineers know a lot about how earthquakes shake and stress modern buildings, and much of that knowledge has already been incorporated into California's building codes to help save lives.

The United State's population has been increasing by almost 1 percent annually due to immigration. With 312 million people, the U.S. is the third most populous country after China and India.

One reason for the continued gloom: It's too hard for many people to qualify for the low rates. But a new program the Obama administration is considering could help millions save an average of $2,000 a year through refinancing.

California is one of a minority of states that doesn't regulate health insurance premiums. State Insurance Commissioner Dave Jones says it's time to change that.