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Patients are protesting, bipartisan lawmakers are threatening regulation – and investors are selling their shares.

Thursday's deadline for federal agencies to submit plans for large-scale layoffs kicks off a new phase in the dramatic restructuring of how the government operates. Here's what that looks like.

San Pasqual Winery is celebrating 15 years at their downtown La Mesa Tasting Room located on La Mesa Blvd. this December with festive wine events for the public to enjoy, including a Vintage Wine Tasting Event from 1 p.m. – 4 p.m. on Saturday, December 7th. The event will feature a tasting of 10 vintage wines from 2009 and beyond. Guests will also have the opportunity to win prizes from local businesses and talk with the owners, Mike and Linda McWilliams, one-on-one. Additionally, there will be a $10 discount on bottle purchases during the event. Tickets for the event are $20 for San Pasqual Winery Wine Club members and $25 for non-members. San Pasqual Winery is San Diego’s first urban winery and produces approximately 3,000 cases of wine each year. The winery sources its grapes from a variety of local and renowned vineyards across California, and produces the wine at La Mesa Wine Works, located in the La Mesa commercial district. San Pasqual Winery is a family owned and operated winery located in La Mesa, Calif. Owners, Mike & Linda McWilliams, purchased the winery in 2009 and have grown it into the thriving business it is today. The winery boasts three tasting rooms, including La Mesa Wine Works, La Mesa Village Tasting Room & Gallery, and Seaport Village Tasting Room. Wine Club membership is also available featuring quarterly wine releases, events and specials. Visit: https://www.sanpasqualwinery.com/ San Pasqual Winery La Mesa on Instagram and Facebook

The San Diego County Regional Airport Authority, which owns and operates SAN, expects to see up to 1.3 million people arriving and departing between Dec. 19 and Jan. 5

From our general session and lunch to the Summit workshops and exclusive after party, you’ll learn, be inspired, and have ample opportunities to get to know like-minded San Diego business owners. Summit workshops feature panels of seasoned, purpose-driven business owners, policymakers, and nonprofit/public sector leaders sharing their perspectives on the topics most relevant to local professionals. Topics include: Business impact on communities Empowering communities with energy access and availability The impact or identity-based business networks How AI will influence small and medium businesses Why you shouldn’t start a nonprofit How media and entertainment are changing Networking with other values-driven professionals in San Diego, including a dedicated “netweaving” session (a deeper way to engage in networking) Office hours with subject matter experts Visit: 2024 (Doing) Business for Good Business for Good San Diego on Instagram and Facebook

Trump's accused the government of Venezuelan President Nicolás Maduro of not meeting democratic conditions for last year's July presidential election as well as of not moving fast enough to transport back immigrants set for deportation.

On Sunday, Feb. 13, 2000, Jane Dorotik’s husband Bob went out for a run and never came back. He was found dead by the side of the road early the next morning, and Jane’s life changed forever. Three days later, she was arrested for his murder. Over the next two decades Jane would become a convict, a martyr, an advocate and she would play a key role in exposing fatal flaws in the criminal justice system.

Art Scene West is exhibiting fine art photography of every genre and showcasing eclectic visual art captured by a camera. On December 14th, we will host an Opening Reception celebrating a collection of photographs highlighting the world's natural beauty, California scenery and incredible landmarks. Our gallery is located in Seaport Village of downtown San Diego, a beautiful attraction where tourists, convention goers, and locals gather to enjoy the seaside businesses, luxury restaurants, and beautiful Southern California weather. Join us in appreciating breathtaking photography as artists, photographers and San Diego creatives come together inside our gallery. Visit: https://www.artscenewest.com/ Art Scene West on Instagram and Facebook

The Tesla brand is in trouble, according to branding consultant Allen Adamson, who says the car company is facing headwinds due to a lack of innovation and the political activity of CEO Elon Musk.

President Trump's new executive order ends collective bargaining for wide swaths of federal employees, as part of his broader campaign to reshape the government's workforce. Unions are vowing to sue.