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Fixing the misfolded proteins that cause dementia and heart failure - Front Row lecture with Jeffery Kelly, PhD Description: All proteins have a correct way of “folding” themselves into their three-dimensional structures. When this folding process goes awry, including processes leading to protein misassembly, a number of devastating diseases can result. In this free Front Row lecture, Scripps Research professor Jeffery Kelly will share how he is developing novel therapeutic strategies to target these protein misfolding diseases, which lead to deterioration of the heart and brain. His multi-disciplinary research has already led to the development of an FDA-approved drug available in the pharmacy called tafamidis (Vyndaqel® and Vyndamax®): a medicine that slows the progression of the neurodegenerative disease familial amyloid polyneuropathy and the degenerative heart disease called TTR cardiomyopathy. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its seventh season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. In 2024 we celebrate a century of turning vision into pioneering impact. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. We hope you’ll join us—in the front row—for the next century of Science Changing Life. Scripps Research on Facebook / Instagram

If the Senate puts up a fight against President-elect Trump's demand for recess appointments, could Trump force Congress to adjourn and ram his nominees through anyway?

Put you knowledge of all things space to the test with these 10 questions — and then earn an official Short Wave badge with your name on it.

Researchers from Oakland University surveyed hundreds of cat caregivers and found that cats exhibited behaviors associated with grief after a fellow cat or dog in the household died.

The Sky Tonight is a live planetarium show held every month in the Heikoff Giant Dome Theater. The Fleet's resident astronomer will lead you on a journey through the cosmos as we explore a new topic each month. The Sky Tonight show on the first Wednesday of every month starts at 7 p.m. or 8:15 p.m. No late seatings. After the night showings, the San Diego Astronomy Association provides free telescope viewing outdoors on the Prado in Balboa Park (weather and operational requirements permitting). NEW! The Sky Tonight: Virtual Edition at 7 p.m. on the third Wednesday of each month, via Zoom NEW! The Sky Tonight: Family Edition at 11 a.m. on the second Sunday of each month Please note late seating or refunds for late arrivals are not permitted. Fleet Science Center on Facebook / Instagram

Some clinics will now check your breast scan for arterial calcification, which can be a sign of heart disease risk. But questions remain about the approach.

Research into some areas of the world that have a lot of centenarians shows that some of those people are no longer alive. Sometimes the fault is bad record-keeping and sometimes it's outright fraud.

For 50 years, a secretive group of government workers has been preparing for the worst. Here's a rare look inside the team that's ready to respond to a nuclear incident anywhere, anytime.

This month's harvest moon will not only coincide with a supermoon, but also with a blood moon and partial lunar eclipse.

The 2024 San Diego Festival of Science & Engineering returns to Snapdragon Stadium on Saturday, March 2, 2024 from 11 a.m. to 5 p.m. This is event is completely FREE and open to the public! No registration or tickets required. Come on down and join us, rain or shine, for a day filled with 100+ hands-on activities, stage performances and more! Great for all ages, pre-K to gray! EXPO DAY MAP FOOD OPTIONS: Various food vendors will be open. There will be two children’s meals available for purchase at Ultra Classics. They are hot dog, bag of chips and 12oz drink OR Uncrustable, bag of chips and 12oz drink for $12. CASHLESS VENUE: Snapdragon Stadium is a cashless venue. We encourage you to plan ahead, but should you need Reverse ATMs, they are available onsite. Reverse ATMs allow for loading cash onto a pre-paid debit card for easy ordering at the cashless concessions. Reverse ATMs are located inside the southeast and southwest gates and will be notated on the event map. FOOD AND BEVERAGE POLICIES: Snapdragon does not allow outside food or beverages into the stadium. Exceptions will be made for those with medical requirements and/or special needs. Water: Sealed water bottles (unfrozen) as well as empty refillable water bottles no larger than 32oz are allowed into the stadium. Water is served at all of the concession stands. Drinking fountains and refill stations can be found throughout the concourse. Water Stations (Refillable): There are five refillable water stations available for guests throughout the concourse. Virtual Resources San Diego Festival of Science & Engineering on Facebook / Instagram