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Scientists Zero in on Alcohol's Effect on the Brain

Scientists Zero in on Alcohol's Effect on the Brain
Scientists at San Diego's Salk Institute have taken a step forward in understanding how alcohol affects the brain. KPBS reporter Tom Fudge explains how this might help fight alcohol dependence.

Scientists at San Diego's Salk Institute have taken a step forward in understanding how alcohol affects the brain. KPBS reporter Tom Fudge explains how this might help fight alcohol dependence.

Scientists say there is a channel for potassium ions in the brain that plays a significant role when it comes to both seizures and the effects of alcohol. Now, Salk researchers have identified a binding point where alcohol interacts with this channel of ions and reduces neuronal activity.

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Neuroscientist Paul Slesinger was the leader of the study, whose results were published in the journal Nature Neuroscience. He says by creating a clearer picture of the effects of alcohol this research could lead to a drug that limits alcohol's effect and, possibly, reduces alcohol dependence. He says making neurons less active, as alcohol does, has unclear effects. But hyperactive neurons can cause seizures. And a drug that fits the alcohol binding point could be a way to treat epilepsy.