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Mainly Mozart – the San Diego nonprofit behind the highly acclaimed Mainly Mozart All-Star Orchestra Festival – is honored to announce Erica Ollmann Saphire, Ph.D., MBA, Professor, President and CEO of La Jolla Institute for Immunology, is the 2025 San Diego Genius Award honoree. Dr. Sapphire will be recognized Oct. 18 at the Genius Awards Dinner at the Westgate Hotel. Tickets are available now at mainlymozart.org/genius. Since 2015, the Genius Award has celebrated extraordinary individuals whose contributions span science, technology, and the arts, enrich the community, and embody “Genius in the Spirit of Mozart.” Saphire joins past recipients Dr. Irwin Jacobs (2015), Dr. Andrew Viterbi (2016), Dr. Walter Munk (2017), Dr. Elizabeth Blackburn (2018), Chancellor Pradeep Khosla (2019), Susan Tousi (2022), Dr. David Brenner (2023), and Dr. Al Pisano (2024). This year’s Genius Award Selection Committee members included Martha Dennis (chair), Steve Hart (chair), Irwin Jacobs, Joel Buxbaum, and David Brenner. Dr. Saphire’s pioneering research at La Jolla Institute for Immunology has unraveled the molecular mechanisms by which viruses such as Ebola, Marburg, Lassa, and SARS-CoV-2 infect human cells and evade immune defenses. Under her leadership, teams have solved the high-resolution structures of multiple viral glycoproteins, guided global vaccine design efforts, and spearheaded the collaborative consortia—including the Bill & Melinda Gates Foundation–supported CoVIC initiative and the NIAID Viral Hemorrhagic Fever Immunotherapeutic Consortium—that united scientists across five continents in life-saving immunotherapeutic research, closing the critical gap between scientific breakthroughs and real-world medical interventions. Recognizing another crucial research gap, Dr. Saphire recently launched a groundbreaking institute-wide initiative focused on uncovering sex-based differences in the immune system. Dr. Saphire’s work has been recognized at the White House with the Presidential Early Career Award in Science and Engineering, with young investigator awards from the International Congress of Antiviral Research, the American Society for Microbiology, the MRC Centre for Virus Research in the United Kingdom, and the California Life Sciences Pantheon Award for Academia and Marion Spencer Fay Award. She has been awarded a Fulbright Global Scholar fellowship from the United States Department of State and a Mercator Fellowship from the Deutsche Forschungsgemeinschaft, to develop international collaborations using cryoelectron microscopy to further global health. Tickets for the gala support Mainly Mozart’s artistic and educational programs, including the Mainly Mozart Youth Orchestra, the All-Star Orchestra Festival and Mainly Mozart’s music education initiatives and community outreach programs, including its long-term partnership with Art of Autism. Mainly Mozart® on Facebook / Instagram

Food and Drug Administration officials say they will ratchet up requirements for vaccine studies, citing concerns about COVID shots for kids. But public health experts question the agency's analysis.

As Pope Leo prepares to visit northern Lebanon, Christian border villages in the south feel abandoned and struggle to rebuild after the war with Israel.

With 284 strings between their instruments, Paul, Vanessa, and Ching-Ming offer a rare alchemy of sound in an inspired program of duets highlighting two luminous partnerships: cello with piano, and cello with harp. From Bach to Mendelssohn, the music moves between warmth and radiance, offering a rich palette of colors and moods. Paul Tseng, cello Ching-Ming Cheng, piano Vanessa Fountain, harp “[Paul Tseng]…poignant and moving… brilliantly executed.” — Spirit of Jefferson Advocate “[Ching-Ming Cheng] has wowed audiences from Taipei to Texas…” — CSUSM News “[Vanessa Fountain] dazzled the audience completely.” — Mariko Hiller, Odeon Chamber Music Series Cello and Harp Adagio - Bach/Marcello Romanze - J. Strauss Sonata in C - Boccherini The Swan - Saint-Saens Meditation from Thais - Massenet Cello Solo Hongyang - Chinese Traditional Cello and Piano Fantasiestücke - R. Schumann Sonata in D - F. Mendelssohn Get Tickets Click here to purchase an Intimate Classics Subscription Package (saves 10-25%). San Diego Music Society on Facebook / Instagram

The Interior Department proposed reviving a suite of changes to Endangered Species Act regulations first made during the Republican's first term. Those changes were reversed under former President Biden.

The San Diego native spent the last nine months traveling and making art. Now he’s back home to debut his first solo show, "One Way Ticket."

Millions of Americans face sharply rising costs for health care plans they bought through the Affordable Care Act marketplaces, unless Congress acts soon. Here's what's at stake for them.

Photographs help us look back on the moments that defined the year. Taken by NPR photojournalists nationwide, this collection goes beyond the headlines to reveal quietly powerful human stories.

07. Halloween Decorations in Plein Air Kevin Inman Saturday, 9:30 a.m.–12:30 p.m. October 25 (1 day, 3 total hours of instruction) On location (either Kensington, Mission Hills or Loma Portal) $90/$110 Back by popular demand! Join Halloween-obsessive Kevin Inman for a pumpkin-spiced painting session in the streets of San Diego. We will paint in San Diego’s top Halloween décor spot of 2025 (if you know, you know) after extensive research by our intrepid teacher. Costumes strongly encouraged; candy provided. Painting outdoors gives the artist the opportunity to experiment with light, color, and atmosphere. Work with San Diego landscape painter Kevin Inman to learn how to paint spontaneously, appreciate nature, and enjoy the moment. Topics include color mixing, design, and letting go of your inner critic. Materials: Recommended oil or acrylic colors (Gamblin and Rembrandt paints): Limited palette: Alizarin Crimson Permanent, Cadmium Yellow Medium, Ultramarine Blue, Titanium White. This palette saves money but limits your options in advanced painting techniques. Basic palette: Cadmium Yellow Medium (or Hue), Cadmium Yellow Deep (or Hue), Cadmium Red Medium (or Hue), Alizarin Crimson Permanent, Ultramarine Blue, Cerulean Blue Hue, Titanium White, Burnt Umber, or preferred alternatives. Recommended but optional palette: Ivory Black, Burnt Sienna, Yellow Ochre. Brushes: a range of brushes from #2 on up. (I prefer hog bristle flats and filberts.) Other: cup or jar for solvent; paper towels; palette or paper palette pad; Gamsol or Turpenoid; linseed oil or Gamblin Solvent-free Gel; sketchbook; pencil; vine charcoal; palette knife; gloves; travel easel or pochade box; hat and sunscreen. Supports: Stack of inexpensive materials for quick studies and exercises, such as a five-pack of Blick canvas boards, size 8” x 10” or 11” x 14”, an Arches oil paper pad, or a canvas pad. Two larger canvas boards or stretched canvases, size 11” x 14” to 16” x 20” for longer projects. Max students: 12 Athenaeum Music & Arts Library on Facebook / Instagram

The proposed constitutional amendment takes aim at two types of taxation common across California.