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Scientists are optimistic that gene-edited animals could provide a new source of organs for transplantation. Pig organs modified to minimize rejection are now being tested in humans.

Where will you be when the clock strikes midnight? With 2023 quickly coming to a close, it's time for us to welcome in 2024! Why not do something a little more exciting and adventurous this New Year's Eve and cruise San Diego Bay aboard Chere Amie's beautiful 90 foot private yacht! Whether you are visiting San Diego for New Years or are a resident here, cruising aboard the Chere Amie is an experience like none other in which you can take in the serenity of the San Diego Bay and amazing views of the city. Witness all the best sights the city has to offer such as the Skyline, Convention Center, and Coronado Bridge. Our yacht comes complete with a full bar, open-view dance floor, and plenty of lounge areas which provide a fun and festive atmosphere perfect for mingling and partying with friends. If you are looking for the ultimate New Year's Eve experience in San Diego, nothing beats being out on the bay. You will be able to see the city of San Diego from a unique perspective while also enjoying everything our yacht party has to offer! This is an exclusive event on one of SD's finest private yachts which makes our NYE party different from other boat parties and events in San Diego. We are limiting the number of spots to this event as we want all of our guests to have the best experience possible. So be sure to reserve your spot before tickets sell out! What we have to offer: - Complimentary boarding glass of champagne - Complimentary appetizers and dessert - Complimentary festive NYE party favors - Live DJ spinning Hip Hop / Pop / Latin Music on the upper deck - 2 Decks which include a Dance Floor, Bar, and Lounge areas - Breath-taking views of the Downtown Skyline, Coronado Bridge, Convention Center, and the beauty of San Diego Bay.. - Today's top hits including Hip Hop and Pop music played in speak-easy environment on lower deck - Fully stocked bar serviced by professional and friendly bartenders(special signature cocktails will be available) - VIP Bottle/Table services For more information visit: cruisesdbay.com

Step into the world of spine-chilling excitement at The Cassara Carlsbad, Tapestry Collection by Hilton! Join us on Thursday, Oct. 26, 2023, at 6 p.m. for an unforgettable SpooktoberFest at the coastal, Mediterranean-inspired property. Prepare yourself for a night of hauntingly good times while you groove to fang-tastic music, savor spine-tingling adult beverages from local vendors, and indulge in delectable Oktoberfest inspired bites. And don't forget your costume! Dress up in your most creative attire for a chance to win spooktacular prizes in our thrilling costume contest. But the thrills don't stop there! We're brewing up exclusive event-only hotel deals that will send shivers down your spine. Save the date and get ready for a night of fun at Spooktoberfest! Limited tickets will also be available at the door on the night of the event. To secure your spot or for more information, please visit https://www.eventbrite.com/e/spooktoberfest-at-the-cassara-carlsbad-tickets-729147027387 Tapestry Collection by Hilton on Facebook / Instagram

As the late night TV genre crumbles under sagging viewership and the decline of traditional media, O'Brien's renaissance provides an example for the future.

Come join us at Chicken Pie Shop to decorate a small pumpkin with succulents, and dried floral materials to make your very own pumpkulent! Included with this workshop is one of their famous mini 2" chicken pies and one mini 2" dessert pie while you create. They offer beer and wine for purchase.

From the theater: Extended by popular demand! Nov. 7 – Dec. 10 Mandell Weiss Theatre By Joe DiPietro Adapted from the novel by Sinclair Lewis Directed by Christopher Ashley You can’t always get what you want, but you might get what you need. Multi-award-winning star of stage and screen Matthew Broderick and Tony Award-winning playwright Joe DiPietro (Diana, Memphis) join forces with our own Christopher Ashley and a stellar cast for this remarkable theatrical event. Babbitt entered the zeitgeist in 1922 as a novel by white-hot satirist Sinclair Lewis, the first American Nobel Laureate. An instant literary classic, Babbitt has been a stalwart on ‘best ever’ lists for over 100 years, and is now adapted for the stage. George F. Babbitt is a middle-aged real estate broker in the Midwestern city of Zenith. By day, he has a prosperous, respectable middle-class existence. By night, he’s plagued by the thought that he has amounted to nothing. Searching for more to life than his top-of-the-line toaster and hickory golf club ― more meaning ― Babbitt leaps with abandon into the most spectacular rebellion of his life ― one that could end up costing him everything. Led by Matthew Broderick in the title role, the cast bringing this world premiere to life features Emmy Award nominee Anna Chlumsky (Veep), Ann Harada (Broadway’s Avenue Q) and Julie Halston (Sex and the City). Ticket discounts: The Playhouse offers a range of ways to save on tickets, including Military, Student and Rush discounts, and $25 tickets in Area 3. Discounts are subject to availability and conditions may apply. Read more here or call Patron Services at (858) 550-1010 for more info. 30 and Under discounts: Area 2 tickets may be available online for $25 with Promo Code CULTUREFIX (limit 2, valid only for will-call with ID). Related links: La Jolla Playhouse website | Instagram | Facebook

SD Royalty Events presents…San Diego’s BIGGEST Quinceañera EXPO! Featuring SoCals #1dance competition & fashion show. Shop for everything that you need at this One Stop Shop featuring 50 exclusive vendors like cakes, decorations, venues, photo booths, DJ’s, party rentals, event planners, caterer’s, florists, limos & party buses, dresses & accessories, makeup artists, dance choreographers and so much more! Sunday, November 5, 2023 from 1-5 p.m. at Julep Venue. Tickets on sale now!

Techniche presents Frequency Featured Resonators - Byrd -Dj K-Swift - Josh Taylor (usa) New Massive, Upgraded Sound System + Lighting 9 a.m. - 2 a.m. For more information visit: themerrow.com Stay Connected on Facebook

Known for fearless, truth-telling lyrics and melodies you can’t resist singing, Emma's Revolution is the award-winning activist duo of Pat Humphries & Sandy O. With one eye on the news, they consistently write songs about critical issues happening in the world and enthusiastically lend their voices to the movements those issues inspire. In their 20th year performing together, their songs have traveled around the world inspiring countless social justice and environmental achievements. Admission is free with registration. For more information visit: emmasrevolution.com Stay Connected on Facebook

Downtown’s The Whiskey House, which holds the Guinness World Record for Most Varieties of Whiskey, is hosting its October Whiskey Club Event on Wednesday, October 18 with Brother's Bond Bourbon of Fort Smith, Arkansas. The evening begins at 6:00 p.m., and it includes a welcome cocktail (blood orange old fashioned), a 1.5-oz pour of each of the three featured whiskeys (Straight Bourbon, Rye Whiskey, Cask Strength Bourbon), and discussions with a Brother’s Bond representative. Food is also included in the price of admission, and the menu will feature charcuterie, Vietnamese wings, and pork sliders. Tickets are $45 in advance. Walk-ins are also welcome, but the price jumps to $55. In addition to street parking, ABM Parking’s BOSA Island Lot is one block away at 450 2nd Avenue.