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The U.S. has registered over half a million clinical trials since 2000. Here's a look at the business and ethics of human medical experimentation through the eyes of a volunteer.

Public health leaders convene in Washington, D.C. this week to defend their vision for America's health, and look ahead for how to rebuild after the Trump administration's attacks on the system.

In addition to hits already in theaters like Wicked: For Good, this holiday week brings sequels for Zootopia and Knives Out.

The sun has burped out bursts of energy called coronal mass ejections that could reach Earth Tuesday night. Forecasters said the vibrant displays could be visible across much of the northern U.S.

The public is invited to join the League of Women Voters of North County San Diego and the LWV of San Diego to hear three experts discuss the ways money and politics influence local entities. Our panel is: Brian Adams, of the SDSU Political Science Department. His book: "Campaign Finance in Local Elections: Buying the Grassroots" examines whether the campaign finance system undermines the capacity of local elections to enhance the democratic character of American elections. Lucas Robinson, investigative reporter for the San Diego Union-Tribune. His work has covered politics, the courts, schools and the pandemic. He will report on his recent investigation of SANDAG's failure to reform no-bid contracting. David Edward Burke, founder of Citizens Take Action. This nonprofit supports policies and programs that enhance the voices of individuals within our political system. As an attorney, he has worked in Congress, coordinated statewide ballot initiatives, and clerked for two Superior Court judges, among other nonprofit work. The public is invited; a Q&A session will follow; light refreshments will be served. League of Women Voters of North County San Diego on Facebook / Instagram

The Court of Federal Claims was a little-known court until the U.S. Supreme Court said that universities need to file suit there, and not in traditional district courts, to try to have their research grant funding restored. The Trump administration has terminated billions of dollars in science grants.

It's impossible to keep up with TV options. These shows are worth catching up on — or revisiting.

Much of the turkey's early history is shrouded in uncertainty, historians and etymologists say — which is particularly true of how the bird got its name.

Independent video game Clair Obscur: Expedition 33 swept the Game Awards last night. The L.A. ceremony draws millions of views for its industry honors and exclusive previews of upcoming games.

Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researchers today.