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Lecture title: Reprogramming the immune system: A new era of precision immunotherapy for cancer and autoimmune disease - Front Row lecture with Travis Young, PhD Description: Your immune system is your body’s natural defense, capable of identifying what belongs and what doesn’t. But when it falters, it can let cancer grow unchecked or mistakenly attack your own healthy tissues, leading to autoimmune diseases. What if we could reprogram the immune system to tip the balance in our favor, gaining an advantage over both cancers and autoimmune disorders? In this free Front Row lecture, Calibr-Skaggs’ vice president of biologics, Travis Young, will share how Scripps Research is using genetic engineering to reprogram patients’ own immune cells to create personalized “switchable” CAR-T cell therapies. This approach represents a new class of precision immunotherapy designed to induce deep and durable remissions in patients with a wide range of cancers, from lymphoma to breast cancer, as well as in chronic autoimmune conditions such as lupus, rheumatoid arthritis and systemic sclerosis. Young will explain how this breakthrough strategy works and what it could mean for the future of medicine. About Scripps Research: Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Facebook / Instagram

We’re kicking off San Diego Comic-Con 2025 with a stellar artist line-up—and you're invited to join us at our Seaport Village Gallery. Friday, July 25 - Sunday, Jul 27, 2025 Friday, 10 a.m. – 7 p.m. Saturday, 10 a.m. – 7 p.m. Sunday, 10 a.m. – 7 p.m. Chuck Jones Galleries (map)

DISCO RIOT will present our latest rendition of our Choreo & ___ program… Choreo & RECESS! Choreo & ___ is a performance plus an activity that allows for people to engage in something physical between short dance performances. This iteration features our (R)evolution Artist Interns as they present site-informed dance work outdoors — exploring themes around bounce, jump, play, games, challenge, and storytelling. During the event, the audience will have the opportunity to engage in family-friendly hands-on activities & games aimed to foster real-time connection with each other. This includes nostalgic playtime activities like jump rope contests, hopscotch and sidewalk chalk art, four square tournaments, and more! Visit: 'DISCO RIOT' presents ... 'Choreo & RECESS' DISCO RIOT on Instagram and Facebook

Crunchyroll is officially headed to San Diego Comic-Con 2025, and it's bringing the massive worlds of anime and music together for Crunchyroll Anime FanFest: a two-day live music festival featuring performances from iconic artists, including SPYAIR, yama, Denzel Curry, INIKO and more! And you won't need a badge to attend. Crunchyroll returns to SDCC "bigger, better and louder" for the event, which will take over The Rady Shell at Jacobs Park behind the San Diego Convention Center for two full days of anime and anime-inspired music on Friday, July 25 and Saturday, July 26. The lineup for Day 1 on July 25 blends iconic talent from Japan's music scene with global, anime inspired music, from electronic to alternative rock: SPYAIR — Japanese rock band behind Haikyu!! The Dumpster Battle theme yama — J-Pop singer behind SPY x FAMILY ending theme. ASH DA HERO — Punk rock band behind “Judgement” for BLUE LOCK Slushii — Anime-inspired DJ, producer, and multi-instrumentalist Magnolia Park — Alternative rock band Hyper Potions — Electronic artist known for anime-esque soundscapes.VGR — EDM producer known for video game and anime music remixesJames Landino — Composer and DJ behind Tower of God original soundtrack Then Day 2 on July 26 showcases anime's impact on hip-hop, R&B and more for fans to explore the interaction between anime fandom and music:Denzel Curry — Miami rapper blending underground hip-hop with anime (and previous guest on Crunchyroll's The Anime Effect podcast!) INIKO — Shonen anime-inspired genre-defying songwriter and producer Pink Pablo — Puerto Rican singer and producer. ALI — Boundary-pushing group behind “Lost in Paradise” for JUJUTSU KAISEN Yaeji [DJ Set] — NYC-via-Seoul artist, producer, vocalist, DJ and lifelong anime fan (also a previous guest on The Anime Effect podcast!)☆Taku Takahashi x Alenoise — DJ and producer of the Black Clover theme NOODLES — Los Angeles-based DJ. The event at The Rady Shell will also host exclusive artist and anime merch pop-ups, plus giveaways and the Activations Crosswalk, which is set to feature immersive experiences from anticipated anime series including Gachiakuta and the return of Kaiju No. 8 and The Rising of the Shield Hero.Crunchyroll Anime FanFest is free for all attendees (no badge for SDCC required!), with doors opening at 1 p.m. on Friday and Saturday. Be sure to lookout for Crunchyroll Team Members and signage to direct you to the entrance.

California over the past dozen years enacted a series of criminal justice laws that were meant to give more people an opportunity to be resentenced and thin out the state’s severely overcrowded prisons.

Assata Shakur, a Black liberation activist who was given political asylum in Cuba after her 1979 escape from a U.S. prison, has died. Officials in New Jersey, where Shakur had been arrested, convicted and imprisoned, said she was 78.

A literary celebration is coming to San Diego. More than 40 award-winning authors are participating in interactive panel sessions and book signings at the inaugural San Diego Book Festival taking place on Saturday, August 23, 2025, 10am - 4pm, on the University of San Diego campus.

On Friday, May 23, the series continues with Jimmy and Enrique, Sue Palmer and Liz Ajuzie, and Walt Richards. Guitarist Jimmy Patton and percussionist Enrique Platas blend flamenco, Middle Eastern, salsa, calypso, Brazilian, and other world rhythms into their fiery, virtuosic performances. Their unique world-music style captivates audiences with intricate guitar passages and exotic percussive rhythms. Known as the Queen of Boogie Woogie, Sue Palmer has been a force in the San Diego music scene for over 30 years. Inducted into the San Diego Music Hall of Fame, Palmer teams up with powerhouse vocalist Liz Ajuzie, whose dynamic voice perfectly complements Palmer’s electrifying piano playing. An expert in guitar and banjo, Walt Richards has been performing and teaching music for over 50 years. He has worked with numerous musical groups, participated in live theater productions, and even won an Emmy for his television work. Jimmy and Enrique Guitarist Jimmy Patton and percussionist Enrique Platas have combined their talents to form this award-winning duo. Their music can be described as having an international flair as they incorporate flamenco, Middle Eastern, salsa, calypso, Brazilian, and other world rhythms into their compositions and arrangements. Their musical collaboration has created a unique, fiery world-music style that has captivated audiences from all over. Listeners will experience virtuosic guitar passages accompanied by exotic percussive rhythms, which together produce a sound that will grab your soul. Sue Palmer and Liz Ajuzie Known worldwide as the Queen of Boogie Woogie, Sultana of Swing, and Lady Who Skates on the 88s, Sue Palmer has been a presence on the live music scene in San Diego and the world for over 30 years. She was inducted into the San Diego Music Hall of Fame in 2018, had a day named after her by the city in 2008, and won numerous San Diego Music Awards for her bands and albums. Liz Ajuzie is a captivating, powerhouse vocalist who has blended masterfully with Sue Palmer in their collaborations in recent years Walt Richards Walt Richards began performing on guitar while still in high school. Within a year he had added banjo, soon becoming one of Southern California's best-known players, with multiple wins at Topanga in the 1960s and 70s. He also toured nationally with the Eddystone Singers and the Appalachians in the 60s. Although offered other opportunities related to his degree, music kept drawing him back and he started teaching guitar and banjo at a San Diego music store in 1963. Walt is celebrating over 50 years of playing and teaching music in the San Diego area. As a multi-instrumentalist and vocalist, he has worked with many diverse musical groups, including doing studio work and live theater (The Old Globe and Starlight theaters in San Diego), besides being a solo and group performer. Earlier work for television earned an Emmy for Walt and partner Vickie Cottle. His most recent television credits include train songs sung for a documentary originally commissioned by Disney.

You are invited you to be a part of the Awesomest Pop Culture and Fandom Convention - the SIXTH Annual Fangaea! Meet up with your posse and make new friends at the Fangaea family friendly fandom festivities! Sci fi, steampunk, comics, cosplay, art, video games, escape room, vendors, martial arts, virtual reality, and much more! We have something for everyone - Fangaea is where Fandoms join forces for fun! Do not miss this return event of what will be the most exciting fandom event of the spring! Taking place Saturday, April 12 and 13, 2025 at the Handlery Hotel in Mission Valley, San Diego, expect an extraordinary experience featuring a plethora of panels ranging from breaking into industry and hands on DIY, to a special cerebral line up of panel discussions. There will be gaming, tournaments, cosplay fashion shows, musicians, vendors, unique apparel, fandom merchandise, virtual reality, pirates, and other special surprises! Stay tuned as we share more fun - keep checking back at www.fangaea.us and www.facebook.com/fangaeacon LIMITED EARLY-BIRD TICKETS AVAILABLE. Kids 8 and under are FREE! PRE-REGISTRATION (through this eventbrite site): Early General Admission Single Day Saturday Ticket - $20 General Admission Single Day Saturday Ticket - $25 Early General Admission Single Day Sunday Ticket - $15 General Admission Single Day Sunday Ticket - $20 Early General Admission Weekend Ticket - $30 General Admission Weekend Ticket - $40 Kids 8 and under - Free ON-SITE PRICING (at the door): General Admission Saturday Ticket (on site, day of price) - $30 General Admission Sunday Ticket (on site, day of price) - $25 Kids 8 and under - Free DISCOUNT CODES ARE NOT VALID ON THE DAY OF THE EVENT.

The major broadcasting groups said in statements the late-night talk show will return to their TV stations on Friday.