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A self-driving car operated by Uber struck and killed a pedestrian in Tempe, Ariz. The incident could be the first pedestrian death involving a self-driving vehicle.

The number of cases is "unprecedented," say medical specialists. Now they're trying to determine why this ongoing outbreak is so large.

The numbers are lower than they were last Thanksgiving.

Veteran aerialist Yann Arnaud slipped off the double rings during a performance and fell 20 feet, according to the theatrical company. He died of his injuries at a hospital on Sunday.

Carmen Schentrup was a senior, one week away from her 17th birthday, when she was killed. Her family reflects on her life, death and why "missing her doesn't feel like enough anymore."

A brand-new pedestrian bridge collapsed onto a highway at a Miami-area college Thursday, crushing at least five vehicles. Several people were seen being loaded into ambulances and authorities said they were searching for people.

After having trouble obtaining drugs needed for lethal injections, state officials plan to change the primary method of execution to nitrogen gas inhalation. It would be a first for a U.S. state.

Opioid overdoses and related deaths are still climbing, according to U.S. statistics. Teasing out which overdoses are intentional can be hard, but is important for treatment, doctors say.

Thirteen influenza-related deaths reported last week have brought the season's total to 302 in San Diego County, health officials announced Wednesday.

A helicopter carrying six people crashed into New York City's East River on Sunday evening, killing all five passengers, while the pilot managed to escape.