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Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives by doing so. But nearly a third of the medicines aren't new or were repurposed many times for financial gain.

Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives by doing so. But nearly a third of the medicines aren't new or were repurposed many times for financial gain.

An investigation by the Justice Department found that Chicago police are poorly trained in use of force, can easily collude to conceal acts of brutality and are rarely punished for violations.

An investigation by the Justice Department found that Chicago police are poorly trained in use of force, can easily collude to conceal acts of brutality and are rarely punished for violations.

The settlement with the Justice Department is tied to a deadly defect in air bags that has been linked to at least 16 deaths. The associated recall is the largest in U.S. auto safety history.

Marie-Antoine Carême died 184 years ago today. But in his short lifetime, he would forever revolutionize French haute cuisine and gain worldwide fame. Some of his concepts are still in use.

Elaine Chao, wife of Senate Majority Leader Mitch McConnell, was President George W. Bush's labor secretary and served in top transportation jobs in the first Bush and Reagan administrations.

U.S. Secretary of the Interior Sally Jewell Wednesday designated 24 new National Historic Landmarks, including Chicano Park in San Diego.

A California appeals court tossed out a law that banned grand juries from determining whether police officers involved in fatal shootings should face criminal charges.

The San Diego County District Attorney announced Tuesday police officers were justified in five separate fatal shootings, including the September 2016 death of Alfred Olango that sparked protests in El Cajon.