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Black Francis, frontman of the Pixies, is trying his hand at literature. He's co-authored an illustrated novel based on the world's first pornographic film, a 1908 production called The Good Inn.

A watch party is planned in Mission Valley as the SDSU Aztecs take on New Mexico State in the 2014 NCAA Men's Basketball Tournament in Spokane, Wash.

Opioid addiction has claimed thousands of lives in San Diego County. Understanding who is dying and how addiction has changed over the last 15 years is central to confronting the region’s epidemic.

The suspected shooter at the Texas Army post is Ivan Lopez, a Pentagon official tells NPR. Authorities say he was being evaluated for PTSD and treated for depression.

Cancer treatment for kids has changed dramatically since the 1960s. Back then, doctors experimented with approaches that seemed promising but were also potentially toxic. Some survivors look back.

Thanksgiving is one day of the year when fewer poor people go hungry in San Diego County because charities overflow with volunteers to serve hot turkey dinners to those in need. But the rest of the year, a half-million people struggle to put food on the table.

Mayor Kevin Faulconer's advisory group is holding the line against Chargers spokesman Mark Fabiani, who is lobbying for a new stadium downtown even though the task force determined the best spot for a new home is Mission Valley.

Many of the 2 million men serving time in the U.S. have formed their sense of manhood while incarcerated. And becoming a different kind of man isn't easy — either behind bars, or beyond them.

He's an epidemiologist. She's a nurse. And both of them felt compelled to head off to West Africa to battle the virus.

One night a week, an empty corner café becomes Moriah Pie. Erin and Robert Lockridge serve homemade pizza, and diners pay what they can. The couple sees their work as God's mission in the community.