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Amanda Anisimova beat Naomi Osaka in the U.S. Open semifinals early Friday in a tense, three-set match. Both players have been climbing up the rankings after taking mental health breaks from the sport.

Lecture title: Expanding the drug target universe - Front Row lecture with Benjamin Cravatt, PhD Description: There are countless proteins that play critical roles in disease, yet they remain challenging to target with therapeutics. In this free Front Row lecture, professor Benjamin Cravatt will explain how his large-scale protein profiling research and innovative chemical technologies are helping identify novel drugs for therapeutic targets previously deemed ‘undruggable.’ Cravatt’s translational work, which is at the intersection of chemistry and biology, has also led to the formation of multiple local biotechnology companies that collectively employ hundreds of scientists who are developing first-in-class candidate medicines for diverse diseases ranging from cancer to neurological disorders. About Scripps Research: Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Facebook / Instagram

Lawrence K. Jackson is the producer and host of KPBS’ San Diego News Now daily podcast.

In a survey of 52 countries, people ranked hope as the most important quality they want from their leaders — ahead of trust, compassion, and stability.

In the face of charges that these strikes amount to execution without trial, the White House is sending a confusing message about who exactly gave each order to use deadly force.

Syria is struggling to heal a year after the Assad dynasty's repressive 50-year reign came to an end following 14 years of civil war that left the country battered and divided.

Special Saturday Matinee! The first film adaptation of J.M. Barrie’s beloved play, "Peter Pan" (1924) almost needs no introduction. The story of a joyous young boy, soaring over a magical land and refusing to ever grow up, has endured through decades and generations. Upon its release, Fred Schader of entertainment industry giant Variety said: “'Peter Pan' is a picture that will go down the years as a delightful fantasy and crop up again and again as time rolls along, and with each return be welcomed with a new joy by a new band of children, who will join the ranks of the never-grownups.” And it’s safe to say, he was right. All children will receive a Balboa Theatre coloring book! This is just one screening in our Silent Movie Mondays series at the Balboa Theatre. Learn more and see the full lineup! San Diego Theatres on Facebook / Instagram

The G20 closed in Johannesburg without a ceremonial hand over to the U.S., its next chair, after Washington boycotted the summit.

Steve Cropper, who co-wrote classics including "(Sittin' on) the Dock of the Bay" and "In the Midnight Hour" during his years playing guitar at the legendary Stax Records in Memphis, has died. He was 84.

President Trump is directing the Justice Department to prosecute his perceived political enemies, upending the career ranks and raising questions about selective prosecution.