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  • Lecture title: Reprogramming the immune system: A new era of precision immunotherapy for cancer and autoimmune disease - Front Row lecture with Travis Young, PhD Description: Your immune system is your body’s natural defense, capable of identifying what belongs and what doesn’t. But when it falters, it can let cancer grow unchecked or mistakenly attack your own healthy tissues, leading to autoimmune diseases. What if we could reprogram the immune system to tip the balance in our favor, gaining an advantage over both cancers and autoimmune disorders? In this free Front Row lecture, Calibr-Skaggs’ vice president of biologics, Travis Young, will share how Scripps Research is using genetic engineering to reprogram patients’ own immune cells to create personalized “switchable” CAR-T cell therapies. This approach represents a new class of precision immunotherapy designed to induce deep and durable remissions in patients with a wide range of cancers, from lymphoma to breast cancer, as well as in chronic autoimmune conditions such as lupus, rheumatoid arthritis and systemic sclerosis. Young will explain how this breakthrough strategy works and what it could mean for the future of medicine. About Scripps Research: Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Facebook / Instagram
  • The new film portrays Hitler's second-in-command, Hermann Goering, as a wily mastermind, sidestepping uncomfortable questions about how unexceptional evil can be.
  • On Sept. 2, 1945, the Japanese and the Allies gathered to mark the official end of WWII. The process went smoothly until Col. Lawrence Cosgrave signed his name on the wrong line.
  • The sanctions sharply escalate tensions with the leftist leader of a country that has traditionally been one of the closest U.S. allies in South America.
  • The Fairgrounds is holding a series of open houses throughout the county through mid-November to get feedback on the site’s master plan.
  • The United Nations Mine Action Service estimates between 5% and 10% of Israeli weapons fired into Gaza in the past two years failed to detonate, and unexploded ordnance has killed at least 328 people.
  • Stream with KPBS+. The series examines how America’s founding turned the world upside-down. Thirteen British colonies on the Atlantic Coast rose in rebellion, won their independence, and established a new form of government that radically reshaped the continent and inspired centuries of democratic movements around the globe.
  • Billboard has revised its system of removing songs from the Hot 100 singles chart once they've gotten too old to qualify as contemporary hits.
  • Brazilian police and soldiers launched a raid on a drug-trafficking gang in Rio de Janeiro on Tuesday, sparking shootouts that left at least 60 suspects and four police officers dead, officials said.
  • Here's where you can find free food, zero-interest loans and other support during the government shutdown.
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