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A Supreme Court case over Louisiana's congressional map could determine the future of Voting Rights Act protections against racial discrimination and allow Republicans to draw 19 more House seats.

Nabarun Dasgupta was recognized with a MacArthur "genius" award for work studying the deadly overdose crisis. He's also a front-line organizer, helping people survive.

The attack took place at the American Fish Company, a bar and live music venue. Police are asking anyone who witnessed the shooting to contact them.

The U.S. has registered over half a million clinical trials since 2000. Here's a look at the business and ethics of human medical experimentation through the eyes of a volunteer.

After decades of planning and setbacks, South Bay officials are laying the groundwork for a multi-university campus that houses academic programs from schools across the San Diego-Tijuana metro.

The announcement follows harsh criticism from the Trump administration about California and other states granting licenses to people in the country illegally.

Investor-owned utility San Diego Gas & Electric (SDG&E) is selling the Sikorsky S-70 Firehawk to San Diego County five years after it bought it.

The U.S. Transportation Department is threatening to shut down thousands of truck driving schools and trainers, part of the Trump administration's widening crackdown on industry.

A section of Interstate 5 in San Diego will be closed starting Friday night and through the weekend as part of the Asset Management Project, which Caltrans calls an effort to preserve existing infrastructure and improve safety.

State Sen. Steve Padilla’s letter comes as Imperial Valley residents and advocates say they were blindsided by plans for the project.