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The FBI is asking amateur detectives to help write the final chapter of a 36-year-old mystery. Last month, the bureau reopened the case of the airline hijacker known as Dan Cooper, who bailed out of a plane with $200,000 in extortion money in 1971.

Why are knee replacements and other orthopaedic surgeries on the rise? We talk to two of the doctors who are participating in The Academy of Orthopaedic Surgeons meeting taking place in San Diego this week.

Surveys show tens of millions of Americans suffer from some form of chronic pain. It's one of the main reasons why people visit a doctor. Those who have chronic pain often get little relief from standard medical therapies. One treatment program in San Diego offers a unique approach that includes counseling, bio-feedback and cooking classes.

Keith Fulton and Louis Pepe are not related by blood and are definitely not physically joined at the hip. But they are that filmmaking oddity of a directing couple. Hollywood'and the Directors Guild of America'seems fine with brothers such the Wachowski's or Farrelly's sharing screen credit at the helm as if the sibling relationship justifies their close collaboration. But unrelated co-directors'especially maverick types like Robert Rodriguez and Frank Miller teaming up for

Has OxyContin abuse in San Diego County been exaggerated? How do you think authorities should handle cases of prescription drug abuse?

"Wild" Bill Donovan, creator of the OSS and credited with creating espionage in this country, was one of the most "exciting and secretive" generals in the U.S. We talk with Douglas Waller, author of a new biography of Donovan.

We'll check up on the health of the San Diego Padres with Scripps Clinic orthopedic surgeon and team doctor Heinz Hoenecke as the team prepares for spring training.

Brent and Kelly King knew something was wrong when they discovered their 17-year-old daughter Chelsea wasn't home. They called her cell phone then her friends. They tried an AT&T Web site and learned her phone had been left inside her 1994 BMW in Rancho Bernardo Community Park, a giant, wooded area on the northern edge of San Diego.

To be the "Greatest of All Time," boxing legend Muhammad Ali says you have to believe in yourself. It's a lesson his parents taught him and it has helped him in fighting Parkinson's disease.

An inspiring new documentary looks at men and women who are living life to the fullest, well into their 90s. We'll talk with filmmaker Susan Polis Schutz and some nonagenarians, including a local artist and writer.