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Former Los Angeles City Councilman Alex Padilla resigned Monday as California secretary of state and was formally appointed by the governor to fill the U.S. Senate seat vacated by Vice President-elect Kamala Harris.

The creators of Harry Potter and the Cursed Child designed their show so it wouldn't look like the world Potterheads knew from the movies. They've documented that process in a new book, The Journey.

More than 1,000 people are serving life sentences in Pennsylvania, even though they never intended to kill anyone — 70% of them are Black. A lawsuit calls the concept cruel and unconstitutional.

Citing ballooning COVID-19 rates and multiple cases of the illness among students in other school districts, leaders of the San Diego Unified School District announced Tuesday they are cautiously looking to Jan. 4 for a major expansion of in-person learning.

As a poor, sick village boy in Ghana, Shadrack Frimpong remembers "praying and saying if I can keep these legs, then I will use them and work to help other people." And that's exactly what he did.

Our roundup of education stories looks at the turmoil following Mayor Bill de Blasio's latest delay announcement; and the continuing struggles on campus to control COVID outbreaks.

With more than 48,000 dead, Africa braces for second wave of the virus and the challenge of affording the potential vaccines.

Interfaith Community Services, serving North County San Diego, is the newest group to purchase a hotel for homeless housing in a commercial zone in the city of Escondido.

The presumptive Democratic nominee now leads President Trump by 11 points. And more people are worried about the coronavirus, but 35% still say they won't get vaccinated when one's available.

NPR was the only news organization allowed into the lab to witness the moment the releases began this year. The goal is to create a powerful new weapon in the fight against malaria.