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There is a good chance these will be the last bids for seats in Congress for two of the best-known women in American politics — Republican icons Liz Cheney of Wyoming and Sarah Palin of Alaska.

The painting is expected to sell for thousands of dollars. The unnamed seller, who found the painting at a donation center in Canada, paid $4.09.

China's support for Russia's war in Ukraine is complicating U.S.-Chinese relations at an already difficult time, U.S. Secretary of State Antony Blinken told his Chinese counterpart.

The San Diego County Board of Supervisors voted 3-0 Wednesday to start the process of allowing micro-enterprise home kitchen operations throughout the county.

Poway Unified School District is considering leasing 27 acres of undeveloped property to Costco, but opponents say officials have violated state law in their quiet push to get the project approved.

The San Diego County Sheriff's Department and the Health and Human Services Agency's Behavioral Health Services division will seek to develop a better way to provide behavioral and physical health services in the county's seven detention facilities.

Retail sales jumped nearly 10% in March, as shoppers, flush with $1,400 relief payments, are feeling more confident about venturing out. Weekly unemployment claims dropped to a pandemic low.

Some patients who have had COVID-19 develop symptoms resembling early Alzheimer's. Researchers are trying to figure out whether these people are more likely to develop the disease itself.

A new study finds that Medicare can be more expensive than other available options, particularly for many people of modest means.

Isolated snow and rain showers are expected to diminish Thursday morning as a cold winter storm moves east and out of San Diego County.