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UC San Diego will be one of the sites for a national COVID-19 vaccine trial slated to begin Monday. Local sites are looking for more than 1,000 San Diegans to sign up. The trial is based on a vaccine prototype developed by Massachusetts-based Moderna Therapeutics. Plus, in San Diego, police officers are often the ones responding to mental health-related 911 calls. We’ll hear about a plan to change that. And, KPBS Arts Calendar Editor Julia Dixon Evans has a preview of this weekend’s top events, beyond Comic-Con@Home.

Wednesday, Aug. 10, 2022 at 9 p.m. on KPBS TV + Sunday, Aug. 14 at 9 p.m. on KPBS 2 / On demand with KPBS Passport! The Big Bang is when the cosmos started and time itself began. With stunning animation based on space telescope images, NOVA winds back the ages to discover new clues about this ultimate genesis and what happened in the universe?s first few seconds.

As a movement to "defund police" travels across the country, one potential target for budget cuts is removing police from mental health calls. Many activists, health officials and some elected leaders say police are the wrong people to be responding to these calls. KPBS reporter Claire Trageser says the details on how that would work are being explored in San Diego County. Plus: the La Mesa Police Department has released body camera footage from a use-of-force incident that left a grandmother blind in one eye, some San Diego gyms are defying County health orders and staying open and more local news you need. San Diego News Matters is KPBS’ daily news podcast. Support the show: https://www.kpbs.org/donate

Sprinter Krystsina Tsimanouskaya told reporters that she was pleading for help from Japanese police at the airport and will not return home to Belarus.

Hugs with friends. Birthday parties indoors. Pillow fights. Kids who got their first shots Wednesday said these are the pleasures they look forward to.

Fewer than 20 percent of veterans suffer from PTSD, but most Americans think the disorder is far more common.

San Diego County health officials reported 1,030 positive COVID-19 cases over the weekend, bringing the region's total to 16,726.

San Diego scientists have zoomed in on the coronavirus and say the virus is coated with a sugary exterior that makes it hard for the human body to fight it. Also on KPBS’ San Diego News Matters podcast: San Diego County public health authorities reported over 300 new COVID-19 cases for the fourth time in five days, unemployment numbers continue to decrease across San Diego County from a high of 25% in May and more local news you need.

Thousands of teachers, nurses and other public servants are learning they could have some of their federal student loan debts erased months — and even years — earlier than expected.

An independent audit of Baja California’s water agency has found that many international companies with operations in Baja California have paid for only a fraction of the water they’ve used for years and have dumped waste without approval into the overburdened Tijuana sewage system. Also on KPBS’ San Diego News Matters podcast: the Chula Vista Police Department is broadening its use of drones, California is moving toward a future when plastics will help build the roads people drive on and more local news you need.