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  • We discuss the recent development changes to the Clairemont Community Plan and what they mean for the neighborhood.
  • Stream now with KPBS+ / Watch Thursday, Oct. 30, 2025 at 11:30 p.m. on KPBS TV. Can we align AI with humanity's interests? Tech companies are racing to develop more powerful models. But when new technology is rolled out without guardrails, the consequences can be disastrous. Tristan Harris joins Ian Bremmer to discuss AI risks.
  • Congress is poised to leave for a scheduled holiday recess without a solution for addressing the expiration of enhanced subsidies for Affordable Care Act marketplace plans.
  • Mainly Mozart – the San Diego nonprofit behind the highly acclaimed Mainly Mozart All-Star Orchestra Festival – is honored to announce Erica Ollmann Saphire, Ph.D., MBA, Professor, President and CEO of La Jolla Institute for Immunology, is the 2025 San Diego Genius Award honoree. Dr. Sapphire will be recognized Oct. 18 at the Genius Awards Dinner at the Westgate Hotel. Tickets are available now at mainlymozart.org/genius. Since 2015, the Genius Award has celebrated extraordinary individuals whose contributions span science, technology, and the arts, enrich the community, and embody “Genius in the Spirit of Mozart.” Saphire joins past recipients Dr. Irwin Jacobs (2015), Dr. Andrew Viterbi (2016), Dr. Walter Munk (2017), Dr. Elizabeth Blackburn (2018), Chancellor Pradeep Khosla (2019), Susan Tousi (2022), Dr. David Brenner (2023), and Dr. Al Pisano (2024). This year’s Genius Award Selection Committee members included Martha Dennis (chair), Steve Hart (chair), Irwin Jacobs, Joel Buxbaum, and David Brenner. Dr. Saphire’s pioneering research at La Jolla Institute for Immunology has unraveled the molecular mechanisms by which viruses such as Ebola, Marburg, Lassa, and SARS-CoV-2 infect human cells and evade immune defenses. Under her leadership, teams have solved the high-resolution structures of multiple viral glycoproteins, guided global vaccine design efforts, and spearheaded the collaborative consortia—including the Bill & Melinda Gates Foundation–supported CoVIC initiative and the NIAID Viral Hemorrhagic Fever Immunotherapeutic Consortium—that united scientists across five continents in life-saving immunotherapeutic research, closing the critical gap between scientific breakthroughs and real-world medical interventions. Recognizing another crucial research gap, Dr. Saphire recently launched a groundbreaking institute-wide initiative focused on uncovering sex-based differences in the immune system. Dr. Saphire’s work has been recognized at the White House with the Presidential Early Career Award in Science and Engineering, with young investigator awards from the International Congress of Antiviral Research, the American Society for Microbiology, the MRC Centre for Virus Research in the United Kingdom, and the California Life Sciences Pantheon Award for Academia and Marion Spencer Fay Award. She has been awarded a Fulbright Global Scholar fellowship from the United States Department of State and a Mercator Fellowship from the Deutsche Forschungsgemeinschaft, to develop international collaborations using cryoelectron microscopy to further global health. Tickets for the gala support Mainly Mozart’s artistic and educational programs, including the Mainly Mozart Youth Orchestra, the All-Star Orchestra Festival and Mainly Mozart’s music education initiatives and community outreach programs, including its long-term partnership with Art of Autism. Mainly Mozart® on Facebook / Instagram
  • A California audit flagged spending mistakes and misuse across multiple agencies, including millions in service fees for unused cell phones. Critics blame weak oversight as the state braces for a potential $18B budget shortfall.
  • Snider's supercharged relationship with her art form and open-book stance on depression and anxiety shine through in her new opera, which debuts this week in Los Angeles.
  • A movie star to his core, Robert Redford has died after a visionary career in cinema, including founding the Sundance Institute that transformed the market for independent films.
  • The countdown has begun for the decaying building in the heart of downtown to either be sold or demolished. The nearly 100-year-old California Theatre has been shuttered since 1990 due to structural safety concerns.
  • Amazon's cloud computing service provides back-end support to many companies that operate online. When it has problems, so do they.
  • This week, passengers began streaming in and out of the airport's new Terminal 1, where public art installations highlight the region’s natural beauty — an unlikely art museum.
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