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A car bomb exploded outside the United States Consulate and a luxury hotel in Karachi, Pakistan's biggest city. The suicide attack killed at least four people -- including an American diplomat. President Bush is scheduled to visit Pakistan this weekend. Renee Montagne talks to reporter Kamran Khan in Karachi.

Secretary of State Condolezza Rice is in the Middle East. Rami Khouri, editor-at-large of the Daily Star in Lebanon, talks with Steve Inskeep about the issues she is facing, including funding for the new Palestinian government and the future of Lebanon.

Iranian negotiators are due to arrive in Moscow Monday for discussions about moving Tehran's nuclear fuel production to Russia. Moscow says its proposal offers the best hope for breaking Tehran's standoff with the West.

Steven Erlanger, New York Times Jerusalem bureau chief, talks with Robert Siegel about claims that the United States and Israel are trying to sabotage the political success of newly elected Hamas officials in the Palestinian government. The U.S. government says it has no such plan to destabilize Hamas.

The Danish government tries to mollify Muslims angry over cartoons depicting Muhammad that were first published in a Danish newspaper. But it has not condemned their publication. As protest continues around the world, Copenhagen is demanding protection for its diplomats and citizens.

A Denmark newspaper's publication of cartoons depicting the Prophet Muhammad has continued to spark protests, despite the government's efforts to contain Muslim anger. Several thousand people rallied in Pakistan Tuesday, burning effigies of Denmark's prime minister.

Parts of the Arab world are still reeling from a furious reaction to the publication of Danish cartoons offensive to many Muslims. The burning of the Danish consulate in Beirut prompts Lebanon's interior minister to resign.

The governing board of the International Atomic Energy Agency meets Thursday in Vienna to consider Iran's nuclear activities. The board is considering a draft resolution offered by Britain, France and Germany that calls on the IAEA to report Iran to the U.N. Security Council. Linda Wertheimer talks to Rob Gifford.

Envoys from the United States, Russia, the U.N. and the European Union consider halting aid to the Palestinian Authority unless Hamas renounces violence and recognizes Israel's right to exist. The militant Islamist group is likely to lead the next government after its success in last week's polls.

Secretary of State Condoleezza Rice heads to London amid a flurry of diplomatic activity over Iran's nuclear program. The U.S. and key European nations want to bring Iran before the United Nations Security Council, and they will be trying to convince Russian and Chinese officials to agree on that step.