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Lecture title: Reprogramming the immune system: A new era of precision immunotherapy for cancer and autoimmune disease - Front Row lecture with Travis Young, PhD Description: Your immune system is your body’s natural defense, capable of identifying what belongs and what doesn’t. But when it falters, it can let cancer grow unchecked or mistakenly attack your own healthy tissues, leading to autoimmune diseases. What if we could reprogram the immune system to tip the balance in our favor, gaining an advantage over both cancers and autoimmune disorders? In this free Front Row lecture, Calibr-Skaggs’ vice president of biologics, Travis Young, will share how Scripps Research is using genetic engineering to reprogram patients’ own immune cells to create personalized “switchable” CAR-T cell therapies. This approach represents a new class of precision immunotherapy designed to induce deep and durable remissions in patients with a wide range of cancers, from lymphoma to breast cancer, as well as in chronic autoimmune conditions such as lupus, rheumatoid arthritis and systemic sclerosis. Young will explain how this breakthrough strategy works and what it could mean for the future of medicine. About Scripps Research: Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Facebook / Instagram

A law firm appealing a stalled case against Tylenol's maker, Kenvue, says people are calling to join the suit, alleging the painkiller caused autism in children whose mothers took it during pregnancy.

The haunting new show from Vince Gilligan, who created Breaking Bad and Better Call Saul, is set in Gilligan's now-signature location, Albuquerque.

There's a lot of talk about how to monitor screen time for kids. But for kids to have healthy relationships with technology and smartphones, parents need to model good habits. Here's how.

Local veterans and political leaders are denouncing a new Pentagon effort to rename the USNS Harvey Milk. Then, attendees of a “Stand up for Science” protest on Friday talked about how federal funding cuts are affecting scientific research. Plus, the candidates in the District 1 county supervisor race differ on their priorities when it comes to the sheriff’s department and the county jails.

"The American Revolution" documentary series by Ken Burns premieres Nov. 16. Two San Diego professors sat down with KPBS' Amita Sharma to discuss what the American Revolution still teaches us today.

The coming months will bring new seasons of Stranger Things and Slow Horses, a mysterious new science fiction series from Apple TV+, and a new Ken Burns documentary about the American Revolution.

Hundreds of people at UC San Diego on Friday attended what they called a “Stand Up for Science” protest, pointing out the harm they think has come from Trump administration cuts.

What happens in Washington doesn’t stay there — it reaches all the way into San Diego’s labs, hospitals, and classrooms. Proposed federal cuts to medical research threaten the life-changing work happening right here in our community. From childhood cancer breakthroughs to ensuring diverse voices shape the future of medicine, local researchers are at risk of losing the support they need to keep pushing science forward. Join the Prebys Foundation and the American Cancer Society Cancer Action Network to hear directly from San Diego scientists and advocates who are stepping up to explain what these cuts really mean — for our families, our health, and our future. But this isn’t just about what’s at stake. It’s about what we can do together. After the panel, you’ll learn simple, meaningful ways to take action. Because once we understand the impact, we can help change the outcome. Will you join us in standing up for science and the people it serves? Agenda: 1 p.m.– Welcome 1:05 p.m. – Panel: “The Human Impact of Research Cuts” & Q and A 2 p.m. – How can we help? Simple ways to support science 2:15 p.m. – Opportunity to Chat 1x1 with participants Parking available onsite. Prebys Foundation on Facebook / Instagram American Cancer Society Cancer Action Network on Facebook / Instagram

Legendary creators, banned books, K-pop fandom, horror deep dives and more — Saturday's Comic-Con lineup as something for everyone. We've grouped our top panel picks by theme to help you plan your day.