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  • Lecture title: The sweet side of drug discovery: How sugars can help shape the future of medicines - Front Row lecture with Yuzhong Liu, PhD Description: Some of the most powerful medicines we use today come from natural products, which are specialized molecules that plants and microbes have evolved over millions of years. Sugars play a key role in these compounds—determining how the molecule behaves, where it travels in the body and how strongly it activates the immune system. In this free Front Row lecture, Scripps Research chemist Yuzhong Liu will demonstrate how her lab uses synthetic biology to decode the role of sugars in medicine—helping scientists build next-generation vaccine adjuvants, cancer therapies and safer treatments. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its ninth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Instagram and Facebook
  • Norwegian police are investigating an explosion outside the U.S. Embassy in Oslo early Sunday, officials said.
  • The second in a series of auctions of Bob Ross paintings to benefit public television stations will take place on January 27, beginning at 9 a.m. PT (12 p.m. EST). The auction will be held at the Bonhams Skinner location in Marlborough, Massachusetts, and will also be available to users live via the online auction site. International auction house Bonhams, in collaboration with American Public Television, will offer a total of 30 original paintings by beloved Joy of Painting host and American artist Bob Ross (1942–1995) across a series of auctions. The paintings were generously donated by Bob Ross, Inc., specifically to benefit public television.100% of the net sales proceeds from the auctions will be directed in support of public television stations nationwide. How to Participate: Those who wish to bid should REGISTER IN ADVANCE AT THE BONHAMS WEBSITE. If you would just like to watch, you can visit the same page shortly before the auction begins. A link to view the sale live will appear about 30 minutes prior to the start of the sale. Registration is not required for viewing only. If you are unsure whether you plan to bid, it is recommended that you register in advance, particularly for new Bonhams clients, to ensure you can participate without delay once the sale begins.
  • This may have been a year when Latin music exploded globally, but the Alt.Latino and El Tiny host also sensed a desire among musicians for softness and stillness.
  • The Maritime Museum of San Diego invites new volunteers to train as docents and help bring maritime history to life at Star of India Wharf. Through an engaging 11-week series of lectures, readings, and guided tours aboard historic vessels, participants learn to interpret artifacts, guide visitors, and share the rich seafaring heritage preserved within the Museum’s fleet. Trainings are held consecutive Tuesdays from 9 a.m. to 1 p.m. from January 20-March 31, 2026 at the Maritime Museum on the upper deck of the 1898 Victorian-era steam ferryboat Berkeley. Share stories, lead tours, and inspire visitors while helping preserve our maritime heritage. No experience needed—just enthusiasm and a passion for the sea! Interested members of the community must register online in advance of training. Registration closes Friday, January 16, 2026. Visit: Docent Training Series Maritime Museum of San Diego on Instagram and Facebook
  • County health officials said the Tijuana River was flowing into recreational ocean waters, prompting concern that sewage contamination could pose health risks.
  • Iran selected Mojtaba Khamenei as the new supreme leader. He is the son of the previous supreme leader. Also on Sunday, the U.S. announced the death of a seventh service member in the war.
  • Macabre Mysterium Presents: "Love at first SLASH!" Roses Are Red, Violets Are Black, Watch Your Step—There’s a Slasher in the back! This Friday the 13th, love comes with a scream. Step into a night where Valentine’s lace tangles with campy slasher bloodlust—because romance has never been so deadly. Date & Time: February the 13th, 2026 | 5 p.m. – 10 p.m. 20+ vendors with eerie, twisted, and heart-stopping creations. The Body Art Bus returns with killer flash tattoos. Blasting rad tunes all night long. Raffles & frightful fun await. New Location: The Lost Abbey 1347 Keystone Way, Ste C Vista, CA 92081 Come dressed in your blood-stained best—whether you’re a doomed lover, final girl, or masked killer, the night is yours to slay. Because sometimes… love doesn’t just break your heart. It slashes it. Macabre Mysterium on Facebook / Instagram
  • Nearly a quarter of teens sleep 5 hours or less per night and the majority sleep less than 8 hours. The problem is pervasive and technology doesn't seem to be the main culprit, according to a new report.
  • D.K. Harrell Guitarist, vocalist and songwriter D.K. Harrell, one of the most formidable young stars of the current blues resurgence, sounds like no one else on the scene today. With his stinging, single-note string bending, deep soul vocals, and attention-grabbing original songs, the 27-year-old Harrell—a major draw at blues festivals around the world—is already in a league of his own. Now, with his Alligator Records debut album, "Talkin’ Heavy," D.K. Harrell cements his place among the leading voices of the new generation of blues players. This Blues Music Award-winning guitarist with a soul man’s voice and a well-earned reputation as a mesmerizing live performer delivers fresh, emotion-packed blues informed by the tradition he loves and played with the foot-pounding fervor of a revival tent preacher. "Talkin’ Heavy" continually surprises with twelve instantly memorable original songs filled with Harrell’s biting guitar work and authoritative, church-born vocals. Produced by studio wizard and musician Christoffer “Kid” Andersen and recorded at Andersen’s now-famous Greaseland Studio, the album shows Harrell as a generational guitar talent with a wide-eyed vision and a street-smart singing style bringing life to the timeless songs he’s writing. He goes deep on the title track, taking a hard look at his surroundings before declaring, “the world is just heavy with the blues.” From blazing album opener "A Little Taste" to the proudly taking-care-of-business "Grown Now" to the feel-good groove of "Vibe With Meto" the foot-stomping closer "Praise These Blues," "Talkin’ Heavy" is an affirmation of the sheer power of modern blues. "With every exuberant turn of phrase, and each sharp guitar lick, the Louisiana born showman displays a pure joy in performing that’s hard to resist. 'Talkin’ Heavy' combines all manner of sounds in one supremely satisfying, engaging package…robust yet relaxed singing and fluid yet piercing fretwork. Ultimately, Harrell’s greatest talent is just being his own larger-than-life self.
" –No Depression "The tube-cookin’, Louisiana-bred guitarist brings the sizzle to 'Talkin’ Heavy,' his new album of Delta-meets-Chicago blues. Harrell makes his mark by wringing every ounce of emotion from a single note before extending the thought with the first of many lyrical, slow-burning, well-crafted guitar solos." –Guitar World "'Talkin’ Heavy' is the joyous sound of a one-man revival. Harrell’s vocals are smooth yet forceful, and his authoritative guitar work — stinging and soulful leads that serve as memorable songs within songs — hits the sweet spot every time." –Guitar Player "Jubilantly raucous, musically adventurous, biting and exploratory…enriched by unselfconscious virtuosity…a leading light of the younger generation of the younger generation of blues artists" –Living Blues "D.K. Harrell is a fast-rising blues dynamo…One of the most talented and exciting young blues artists to emerge in decades." –San Diego Union Tribune TARYN DONATH DUO An accomplished musician who has been performing professionally for over 25 years, Taryn has an incredibly commanding performance style….each live performance is exciting and spontaneous. Her piano playing is tenacious and purposeful, while her voice is smooth, sultry, and unique to her. Taryn lights up the stage every time she plays. Currently, Taryn has been performing as a duo with a drummer… Fresh, unique and exciting the two play anything from 60’s soul jazz, funk, jump/swing, Latin, and their own term of beatnik blues taking the listener on a musical adventure. With an unwavering left hand, a right hand that weaves in and out effortlessly, and a backbeat as solid as a rock, the Duo has a sound larger than life. Each performance is different from the last, capturing the moods of the players. The two are not bound by rules, but instead have a desire to express their own musical voice and deliver something captivating. “I look forward to creating something unique each time I play.”- Taryn D.K. Harrell on Facebook / Instagram
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