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This weekend in the arts in San Diego: New visual art from Brandon Eugene Secrest and Leslye Villaseñor; visual artist Hugo Crosthwaite's chamber music collaboration; the San Diego Asian Film Festival; printmaking in Oceanside; "El Alebrije" and more.

Join us in person this year for the best darn 4th of July of all time. We’ve got a lot to celebrate, Scripps Ranch. Run or Ride any time between these dates. Wear your Freedom Run & Ride bib to encourage others to honk and wave! Dress up, take pictures, videos and show your 4th spirit by posting to our Scripps Ranch 4th of July Run & Ride community Facebook page. Red, White, and You. After you cross the finish line, the fun is just beginning. Join us in Hoyt Park for the best after party in town where we’ll have live bands, a (free!) craft beer garden, bounce house, inflatable slide, silent auction, face painting, sponsor booths, treats for the kids, and so much more. Visit: 4th of July Run and Ride Scripps Ranch Run and Ride on Instagram and Facebook

Researchers said the correlation between poor water and air quality validates what residents have said for years: exposure to the pollution is not just a nuisance, it’s causing their health issues.

Lecture title: Regenerative medicine for the treatment of MS: Enhancing repair to prevent progression Front Row lecture with Luke Lairson, PhD Description: Multiple sclerosis (MS) is a debilitating autoimmune disease that disrupts the central nervous system, causing symptoms like muscle weakness, cognitive challenges and a gradual loss of function that current treatments cannot fully repair. MS arises when the immune system attacks the myelin sheath, the protective layer insulating neurons. Scripps Research chemistry professor Luke Lairson will discuss his research on the body’s natural repair pathways—specifically those that activate endogenous stem cells to restore myelin. His work aims to develop therapies that complement existing therapeutic approaches and halt MS progression. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Scripps Research on Facebook / Instagram / TikTok

June 16 (at Scripps Research) features the all-star duo of bassist Dave Holland and Lionel Loueke on guitar and voice, playing music from their forthcoming release, "United." Holland makes a long-awaited return to the Athenaeum series, having last performed at the Scripps Research Hall in 2007. Holland’s passion for musical expression of all styles has propelled a career of more than 50 years and earned him top honors, including multiple GRAMMY awards and the title of NEA Jazz Master in 2017. His virtuosic technique and rhythmic feel are widely revered and in much demand. To date, his playing can be heard on hundreds of recordings, with more than 30 as a leader under his own name. Loueke last appeared at the library in summer 2023. A native of Benin, he came to the United States on a scholarship to Berklee College of Music and from there gained acceptance to the Thelonious Monk [now Herbie Hancock] Institute of Jazz in Los Angeles. Praised by his mentor Hancock as “a musical painter,” Loueke combines harmonic sophistication, soaring melody, and conventional and extended guitar techniques to create a warm and evocative sound of his own. The duo of Holland and Loueke embodies a soulful conversation between two masters, merging their unique voices into something beautifully transcendent. The album is a profound testament to true collaboration, beautifully fusing Loueke’s rich West African roots with Holland’s profound influence on modern jazz. Visit: https://www.ljathenaeum.org/events/jazz-25-0616 Dave Holland on Instagram and Facebook Lionel Loueke on Instagram and Facebook

Last year, four measles cases were confirmed in the county, all associated with international travel.

We're excited for our upcoming Jeffrey B. Graham Perspectives on Ocean Science Lecture — Indigenous Ocean Culture: A Renaissance — with Stan Rodriguez (Iipay Nation of Santa Ysabel), Priscilla Ortiz (Iipay Nation of Santa Ysabel and descendant of Rincon), Andrew Pittman (Los Coyotes Band of Cahuilla and Cupeño Indians and Iipay Nation of Santa Ysabel) and Nan Renner (Senior Director of Strategic Partnerships, Birch Aquarium at Scripps)/The land we now call Scripps Oceanography has been home to the Kumeyaay people for thousands of years. A history of encroachment, colonization and displacement from coastal lands has challenged Kumeyaay ocean traditions and practices. Today, Kumeyaay-Iipay-Tipay people are actively revitalizing Indigenous ocean culture. Through community efforts, they are rebuilding traditional ha kwaiyo (tule boats), harvesting ha shupill (grunion) and teaching language about the ocean (ha silowik). These intergenerational practices embody Indigenous resilience, resistance and revival — nurturing and evolving Indigenous ocean knowledge, culture and traditions. Visit: https://aquarium.ucsd.edu/events/perspectives-lecture-series-april Birch Aquarium at Scripps on Instagram and Facebook

Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researchers today.

Delayed federal guidance is limiting access to the updated COVID-19 vaccine in San Diego County.

We look into what the Trump administration's latest spending cuts could mean for the future of HIV and AIDS programs and vaccine research, both on an international and local level.