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Machado received a standing ovation from the crowd at Petco Park, where he’s been a fan favorite since joining the Padres as a free agent in 2019.

Lecture title: Regenerative medicine for the treatment of MS: Enhancing repair to prevent progression Front Row lecture with Luke Lairson, PhD Description: Multiple sclerosis (MS) is a debilitating autoimmune disease that disrupts the central nervous system, causing symptoms like muscle weakness, cognitive challenges and a gradual loss of function that current treatments cannot fully repair. MS arises when the immune system attacks the myelin sheath, the protective layer insulating neurons. Scripps Research chemistry professor Luke Lairson will discuss his research on the body’s natural repair pathways—specifically those that activate endogenous stem cells to restore myelin. His work aims to develop therapies that complement existing therapeutic approaches and halt MS progression. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Scripps Research on Facebook / Instagram / TikTok

Takahiro Shiraishi, known as the "Twitter killer," was sentenced to death in 2020 for the killings in 2017 of the nine victims, most of whom had posted suicidal thoughts on social media.

San Diego-based Navy senior chief Ben Kibler was going to advance into a highly selective officer program this year. That is until the Secretary of Defense Pete Hegseth labeled those with gender dysphoria "incompatible with the high mental and physical standards necessary for military service."

When it comes to clearing homeless encampments, California cities are governed by a patchwork of very different policies.

Producer Lorne Michaels has said he is looking to shake things up ahead of SNL's 51st season, which starts Oct. 4.

Attorney General Pam Bondi said in a directive issued Thursday evening that DEA boss Terry Cole will assume "powers and duties vested in the District of Columbia Chief of Police."

The San Diego Automotive Museum is proud to announce its second annual Cruising for Drivers Golf Tournament, presented by Barnhart-Reese Construction, Inc. This exciting event will take place on Monday, May 19, at Coronado Municipal Golf Course (2000 Visalia Row, Coronado, CA 92118), offering a day of friendly competition, camaraderie, and community impact. Attendees will enjoy an unforgettable day at one of the nation’s top ranked public courses surrounded by breathtaking views of the Coronado Bay Bridge, San Diego harbor, and downtown skyline. With a scramble format, this event is designed for golfers of all skill levels and features a hole-in-one competition, golf swing analysis, “Pay a Pro” opportunities, a PXG golf hole challenge to win a PXG driver, and a raffle with exciting prizes. Participants will also be treated to lunch, craft beer, margaritas, and other festivities throughout the day. The tournament will commence at 10:30 a.m. with a meet and greet, followed by a 1 p.m. shotgun start and 18 holes of golf, closing at 5 p.m. with an awards ceremony and reception. Proceeds from the tournament will directly support the Museum and its programming, including IGNITE Academy, an innovative education program that equips underserved San Diego youth with technical skills, mentoring, and pathways to career success in the automotive industry and beyond. This event is presented by Barnhart-Reese Construction, Boss Construction, and Greater San Diego Air Conditioning. Registration is now open. Pricing for foursomes starts at $1,200. Sponsorship opportunities are also available. Secure your spot today Visit: https://sdautomuseum.org/pages/cruising-for-drivers-golf-tournament San Diego Automotive Museum on Instagram and Facebook

The State Department is slashing hundreds of jobs in what's being called its biggest shake-up in decades — drawing sharp criticism from former diplomats who say the cuts risk gutting America's diplomatic muscle.

Coping with cancer and its aftermath isn't easy for anyone. But men tend to isolate more, seek less support and, alarmingly, die earlier than women. Young survivors are working to change that.