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Lecture title: How microbes are rewriting the rules of immunity - Front Row lecture with Howard Hang, PhD Description: How do microbes influence our immune system, and can we leverage this relationship to combat disease? In this free Front Row lecture, Scripps Research Professor Howard Hang will delve into his lab’s innovative work at the intersection of chemistry, microbiology and immunology. By dissecting the molecular dialogues between gut bacteria and human cells, Hang’s research uncovers how microbial enzymes generate small molecules—called microbial metabolites—that can influence immune responses. These insights are paving the way for new treatments against infections, cancer and inflammatory illnesses, highlighting the powerful role that microbes play in shaping human health. About Scripps Research: Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Facebook / Instagram

With tradition in his touch and vision in his phrasing, the captivating pianist Aaron Diehl leads a trio that moves with quiet intensity and refined power. Along with a top-notch drummer and bassist tuned perfectly to his style, Diehl crafts performances that balance the soul of early Romanticism with the pulse of modern jazz—inviting listeners into a space where every note speaks, and the music connects like a conversation. Visit: https://theconrad.org/events/aaron-diehl-trio/ Aaron Diehl on Instagram and Facebook

"The Servant of Two Masters" is a laugh-a-minute screwball comedy. Based on the original commedia dell'arte play, AJ Knox and Samantha Ginn have adapted the production for new audiences, inspired by comedy classics like "Airplane!", "The Marx Brothers" and "Monty Python." When the trickster Truffaldino signs on to serve two masters in the hope of double wages and double dinners, chaos and hilarity ensue. Translated by AJ Knox Adapted by Samantha Ginn and AJ Knox Based on the play by Carlo Goldoni Directed by Geno Carr Visit: https://gcccd.universitytickets.com/w/event.aspx?SeriesID=45

Shelby isn’t your average Viking-in-training. Sent off to slay a dragon, Shelby has zero interest in swinging a sword—their dream is to become a pastry chef! Along the way, Shelby crosses paths with quirky mythological creatures and discovers that sometimes the greatest adventure is daring to be yourself. This playful, big-hearted tale is perfect for the whole family. By Omri Schein Directed by Shana Wride Grossmont College Theatre Arts on Instagram

Recital Hour at Mesa College lights up your Wednesdays with live performances in Music C-119, every week while school is in session. Open to all and always free, this series brings the joy of music to students and the wider community alike. Windscape promises a refreshing musical journey through the works of Beethoven, Mahler, Ulikhanyan, Shostakovich, and Arutiunian – a rich blend of timeless classics and bold, lesser-known gems. When: October 22nd, 3 p.m. - 4:20 p.m. Where: Mesa College, Room Music C-119 San Diego, CA 92111 Visit: https://www.finestmusic.org/events/windscape-at-mesa-college Windscape

Skinshape is the studio project of British musician and producer William Dorey. Skinshape grew out of a love for old music and the way it sounded. The sound has roots in many genres, but in particular 1960s-70s Funk, Soul, Reggae, Psychedelic Rock, Afrobeat and Folk. He also played with the band Palace as bassist from 2014 - 2017, and is the co-founder of a reggae label called Horus Records. Visit: https://www.ticketweb.com/event/skinshape-sons-of-sevilla-belly-up-tickets/14284743?pl=bellyup&REFID=bupwebsite Skinshape on Instagram and Facebook

1 Night. 17 Stops. Endless Fun! Thursday, September 11 | 6 p.m. - 9 p.m. Check-in begins at 5:45 p.m. at Old Town Market 4010 Twiggs St. or Casa Guadalajara 4105 Taylor St. Prepare your taste buds for an unforgettable journey through the charming streets of historic Old Town San Diego! This culinary extravaganza offers a unique opportunity for guests to indulge in the rich flavors and diverse cuisines that make this neighborhood a local gem. As you embark on your self-guided tour, you'll receive a comprehensive map that will guide you to the very best Old Town restaurants. The participating restaurants will showcase their signature dishes and offer tantalizing samples for guests to savor. For those seeking an enhanced experience, upgrade your tickets with the Tequila Tour. You will be treated to a sample cocktail from select participating restaurants. Sip on expertly crafted margaritas, innovative craft cocktails, or refreshing mezcal creations as you delve deeper into the vibrant flavors of Old Town. Visit: https://www.oldtownsandiego.org/taste/

The music of Eric Clapton's 55-year career ranges from Delta Blues ("Crossroads") to Psychedelic Rock ("White Room') to pop standards ("Wonderful Tonight" and "Tears In Heaven"). "The Core" perform an electric and acoustic tribute to Eric Clapton - from Cream ("Sunshine of Your Love") through Blind Faith ("Can't Find My Way Home") and Derek and The Dominoes ("Layla") into his extensive solo career ("I Shot The Sheriff", "Lay Down Sally"). Visit: https://www.ticketweb.com/event/the-core-eric-belly-up-tickets/13824624?pl=bellyup&REFID=bupwebsite The Core - Eric Clapton Tribute on Facebook

El Cajon is one of just two cities in California fighting state immigrant sanctuary laws. This year the city council passed resolutions supporting President Trump’s deportation campaign. Then, the days of RV’s parking in Mission Bay long term may be numbered. And, clean air vehicle stickers are set to soon expire, but a proposal could change that. Finally, we take a look into how the rise of AI has also brought with it numerous copyright lawsuits.

Ronstadt Revival is the premier tribute to Linda Ronstadt, with a full 7 piece band, including fiddle and pedal steel, to bring you the true authentic sound of the Ronstadt catalog. Real, raw and 100% LIVE music. From Linda's 1967 beginnings with "The Stone Poneys", to her amazing renditions in the 70s of songs by beloved songwriters like Smokey Robinson, Warren Zevon, Lowell George, The Eagles and The Rolling Stones, to her 80s smash album "Mad Love" with its New Wave vibe. Ronstadt Revival will take you on a timeless journey of all of your favorites including, "You're No Good", "Blue Bayou", "When Will I Be Loved", "Tracks of My Tears" and so much more! Visit: https://www.ticketweb.com/event/ronstadt-revival-belly-up-tickets/14486453?pl=bellyup&REFID=bupwebsite Ronstadt Revival on Instagram and Facebook