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The California State University system decided in late July to require students to get a COVID-19 vaccine. Unfortunately for students, the deadline to get vaccinated and the start of classes conflict in potentially problematic ways.

Persistent cross-border sewage flows are prompting state water quality regulators to demand action from the U.S. federal government.

The worst flooding in decades to affect Germany and parts of Belgium has killed more than 100 people as search and rescue efforts for hundreds of missing continue, officials said.

Asylum seekers to the U.S. will keep being sent to Mexico, despite the program being deemed illegal by the Court of Appeals. Plus, a nearly billion-dollar housing bond moves forward in San Diego. And San Diego homeless providers try to address the coronavirus.

San Diego scientists have diagnosed a patient with a new form of a rare disease - they say he's the only known person in the world with it. And California scientists are seeing how warmer oceans might impact fish communities living near the ocean floor.

The coronavirus outbreak is creating big-budget unknowns for cities, the county and schools. The future of billion-dollar budgets is unclear as local governments, schools respond to the virus. And gun stores are seeing record sales during the coronavirus outbreak, but are they allowed to stay open under Gov. Newsom's orders? Plus, the hospital ship USNS Mercy left San Diego Monday bound for Los Angeles in support of the nation's pandemic response efforts.

San Diego County health officials are now ordering essential workers who interact with the public to wear face masks and recommending residents to cover their faces when leaving home. Plus, San Diego County Democratic Party Chairman Will Rodriguez-Kennedy shares his battle with COVID-19. Also, the coronavirus doesn’t seem to be affecting young children as much. Rady Children’s Hospital infectious disease specialist Dr. Mark Sawyer explains why. And, our film critic Beth Accomando has some suggestions for movies to take your mind off the pandemic.

A second group of passengers from the Grand Princess cruise ship, on which at least 21 people tested positive for coronavirus, is expected to arrive Tuesday at Marine Corps Air Station Miramar to begin a two- week quarantine period.

A fight between Republicans has punctuated the race for the seat of disgraced California GOP Rep. Duncan Hunter.

Officer Bryan Riser, 36, was charged with capital murder in the deaths of a 61-year-old man and a 31-year-old woman, Dallas Police Chief Eddie García said at a Thursday media briefing.