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We'll hear an update on Camp Pendleton-based Marines in Afghanistan from Tony Perry, San Diego bureau chief for the Los Angeles Times, who just returned from the Helmand Province.

What are the biggest challenges facing Camp Pendleton-based Marines who are currently serving in Afghanistan? We discuss how the conflict in Afghanistan is different, and in some ways more challenging than the war in Iraq. Plus, we'll talk about what benchmarks need to be achieved before U.S. combat troops can withdraw from Afghanistan.

Opponents of Proposition D are hoping to prevent the sales tax/reform measure from appearing on the November ballot. We discuss why the "No on D" supporters are asking a judge to remove the ballot measure. We'll also talk about why advocates for Proposition D think it is crucial city voters pass the measure in November.

The Seattle Gum Wall, the Montana Testicle Festival, and the entire state of Nevada are just a few of the non-destinations Catherine Price lists in her anti-travel guide, 101 Places Not To See Before You Die. Price takes it upon herself to go to terrible tourist destinations ... so you don't have to.

Chances are you've never heard of Charles and David Koch. The brothers, worth billions, are major industrialists and generous philanthropists. But in Washington, as Jane Mayer writes in the Aug. 30 New Yorker, they're "best known as part of a family that has repeatedly funded stealth attacks on the federal government, and on the Obama administration in particular."

Airs Friday, August 27, 2010 at 10 p.m. on KPBS TV

What are the benefits and downsides of synthetic biology? We'll explore the ethical issues that arise as part of our monthly ethics segment.

Horror Fest Comes to San Diego

American Military Suicides Increasing

In past recessions, home sales helped lead the economy out of trouble. But this time, the economy may have to pull home sales out of the woods, rather than the other way around.