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Matteo Renzi had pinned his political future on the proposed constitutional changes, which would have taken some power away from Italy's Parliament. Renzi announced he will resign on Monday.

Among the winners were Colson Whitehead's The Underground Railroad for fiction, The Washington Post's David Fahrenthold for national reporting and The East Bay Times for breaking news reporting.

The future of the San Diego Opera may still be up in the air, but a new report shows arts and cultural organizations have a major impact on San Diego's economy.

San Diego philanthropist Conrad Prebys, whose donations have supported major projects in San Diego, has died of cancer.

Authorities also seized drugs in the ongoing investigation of the Tau Kappa Epsilon fraternity

Ke Jie is a wunderkind — the 19-year-old undisputed master of what might well be the world's most complex game. And he just soundly lost a best-of-three series to an artificial intelligence program.

The highest marks for overall tobacco control were given to El Cajon and Solana Beach, each of which received a B grade. Imperial Beach, La Mesa, Lemon Grove, Oceanside, Poway, San Marcos and Santee were each given F grades.

The ban is unlawful, discriminatory and arbitrary — and hurts business, say 97 tech companies ranging from Apple and Facebook to Google and Uber.

Virginia Rep. Randy Forbes is now the second Republican incumbent to lose in a primary this year, the victim of mid-decade congressional redistricting.

Opera performed during Holocaust in Theresienstadt