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Lawyers for the Mt. Soledad Memorial Association on Tuesday filed a petition to send a long-running court battle over the fate of a 43-foot cross in the hills above La Jolla directly to the U.S. Supreme Court.

Research suggests that a shot every one to three months may someday give an alternative to the daily pills that some people take now to cut their risk of getting HIV from sex with an infected partner.

The Council voted to increase the fee late last year by a 5-4 margin. Business leaders who oppose the increase, including former mayor Jerry Sanders, call it a "jobs tax" and gathered enough signatures to force Council action.

Shelley Zimmerman was unanimously confirmed by the San Diego City Council on Tuesday as the first female chief of the San Diego Police Department.

Hundreds of Zelda players were able to cooperate enough to beat The Legend of Zelda three times over in less than a week. Here's how.

More than 2,000 premature deaths and about 50,000 cases of kids with respiratory problems will be avoided by 2030 if the new emission rules go into effect, the EPA said.

Women's History Month: 2014 Honoree

The teenage years are the last golden opportunity to build a healthy brain, researchers say. So smoking pot might not be so smart.

Ever wonder what a city proclamation actually is, and where they come from? Want to see all 700 from 2013?

Studies show regular marijuana use by teens — once a week or more — affects areas dealing with memory and problem solving. That can hurt cognition and academic performance.