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Lecture title: The sweet side of drug discovery: How sugars can help shape the future of medicines - Front Row lecture with Yuzhong Liu, PhD Description: Some of the most powerful medicines we use today come from natural products, which are specialized molecules that plants and microbes have evolved over millions of years. Sugars play a key role in these compounds—determining how the molecule behaves, where it travels in the body and how strongly it activates the immune system. In this free Front Row lecture, Scripps Research chemist Yuzhong Liu will demonstrate how her lab uses synthetic biology to decode the role of sugars in medicine—helping scientists build next-generation vaccine adjuvants, cancer therapies and safer treatments. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its ninth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Instagram and Facebook

The Center for World Music presents Mbira Bhururu: Songs of the Shona People of Zimbabwe at La Jolla Community Center. Experience the rich cultural and musical heritage of Zimbabwe through the traditional sounds of the mbira (Zimbabwean “thumb piano”), accompanied by the rhythmic pulse of hosho shakers. Played for over a thousand years, the mbira has been central to Shona spiritual ceremonies, storytelling, and community gatherings. The ensemble Mbira Bhururu offers audiences an exploration of the instrument’s intricate layered melodies, the interplay between rhythm and tune, and the ways music fosters cultural continuity and connection to ancestry. During the audience Q&A following the concert, attendees will have the opportunity to engage with the musicians, learning about Zimbabwean musical traditions and the ways these artists carry forward a centuries-old cultural legacy. Center for World Music on Facebook / Instagram

Beginner workshops are perfect for you to grab your friends, grab a drink and come make tiny trees! We’re bringing the awesome art of bonsai out of the hedged in gardens and into the streets! Or at least into your favorite bars/breweries/pubs. Bonsai Bar is a night of fun you don’t want to miss. Learn the fundamental skills and techniques behind the art of bonsai while enjoying a night out with friends! Our teachers will introduce core concepts and guide your experience as you pot, prune, and design your very own bonsai tree! Our Guarantee: These tiny trees are so hardy we guarantee you can keep yours alive, or we’ll replace it. This workshop will be hosted at Societe Brewing Company. Societe was founded in 2012 on the idea that beer is the world’s greatest social uniter. This mindset inspired our name and it keeps us focused on every ounce we brew. We see our brewery as a vehicle for bringing people together from all walks of life. Beer by beer, we’re working hard to build our community, starting with our rally cry– BEER FOLK UNITE! Under 21 policy: Please contact Societe Brewing Company for details regarding underage entry For more about Bonsai Bar and what to expect at our classes, visit our website at: https://bonsaibar.com/products/societe-brewing-company Happens on the following Dates: Aug 26, 2025, 6 p.m. to 8 p.m. Timezone: PDT Sep 23, 2025, 6 p.m. to 8 p.m. Timezone: PDT Oct 21, 2025, 6 p.m. to 8 p.m. Timezone: PDT

A new program at the Department of Energy is pushing the development of nearly a dozen new reactor designs at breakneck speed.

The La Jolla Concours d'Elegance returns for an extraordinary three-day seaside experience where world-class automobiles, fine dining, art, and culture converge overlooking the Pacific Ocean. More than a car show, the La Jolla Concours is a curated luxury weekend-a gathering of collectors, designers, historians, and tastemakers drawn together by craftsmanship, performance, and beauty. Weekend Highlights VIP Opening Soirée Friday, April 24 | 6–10 p.m. | 21+ Begin the weekend in style with an exclusive coastal soirée featuring: - Handcrafted cocktails from expert mixologists - Culinary creations by San Diego's top restaurants - Chic live music and elevated ambiance - Rare vintage automobiles on display - Live auction with unique collectibles Dress to impress-this is La Jolla elegance at its most modern. Porsches and Power on Prospect ------------------------------ Saturday, April 25 | 5–9 p.m. Prospect Street transforms into a vibrant open-air showcase featuring: - Legendary Porsches, exotic supercars, and hypercars - Live music, gallery receptions, and retail specials - Specialty dining and cocktail menus throughout the village An immersive celebration of speed, design, and La Jolla nightlife. (Dining reservations recommended.) La Jolla Concours d'Elegance - Flagship Event ------------------------------ Sunday, April 26 | 9 a.m.–4 p.m. Widely regarded as one of the finest classic automobile showcases in the United States, the Concours brings together 170+ meticulously curated vehicles from around the world-spanning pre-war classics, racing legends, and one-of-a-kind international icons. Set on the lawn above La Jolla Cove, collectors compete for Best of Show, judged on elegance, technical merit, and historical significance. Enjoy: - Live music and docent-led tours by automotive historians - Champagne and Honey Tasting Garden - Coastal ocean views unlike anywhere else - Chef tastings, premium wines, and craft cocktails VIP and Collector Experiences ------------------------------ - VIP Ocean Suite with lounge seating and bottle service (limited availability) - Commemorative poster signed by renowned automotive artist Scott Jacobs - Early access, exclusive hospitality, and premium viewing areas 100% of net proceeds benefit the La Jolla Historical Society This is where automotive artistry meets coastal luxury. This is where you become part of the show. Tickets, VIP experiences, and vehicle registration: LaJollaConcours.com La Jolla Cove, California April 24–26, 2026 Early purchase strongly recommended-VIP experiences are limited. Date and Time: On Friday, 24 April 2026 9 a.m. - Sunday, 26 April 2026 11 p.m. Venue details: La Jolla Cove, San Diego, California, 92037, United States Price: Tickets Starting from: $29 La Jolla Concours d'Elegance on Facebook / Instagram

Federal agents are accused of using dangerous driving tactics during immigration enforcement. Their vehicle pursuits have been blamed for crashes and at least one death.

Iran's foreign minister arrived in Islamabad, and the White House says Steve Witkoff and Jared Kushner will go there Saturday to try to "move the ball forward towards a deal."

Crafted by Claire and Tyler, The Holiday Series launches Friday, November 28 and makes a thoughtful gift for home bakers, dessert lovers, and anyone assembling a holiday dessert table. The series is available in all Salt & Straw shops and for national shipping, and features ice cream interpretations of two beloved Claire recipes: Pineapple Upside-Down Cake — a holiday twist on à la mode, with chunks of pineapple cake folded into sweet-cream ice cream and drizzled with gooey rum butterscotch Chewy Molasses Cookies with Rum Caramel — salted vanilla ice cream ribboned with rum-spiked caramel and packed with crushed molasses cookie Rounding out the pack are new and returning flavors from Tyler: Peppermint Cocoa with Crushed Candy Canes Almond Brittle with Salted Ganache The Great Cookie Swap Salt & Straw will also be running several promotions throughout December, kicking off with their Cyber Week promotions (12/1–12/5) – $10 credit towards shipping from any online pint or subscription purchase and $10 giftcard for any $40+ Order Head purchase. For the Winter Solstice on December 21, all scoop shops will be running a “Make It A Double” upgrade for single scoops, eligible for anyone who mentions the promo when ordering. In case you’re looking for other gifting ideas or shippable foods for the season, we also wanted to share some of Salt & Straw’s additional holiday-ready offerings: Almond Brittle Cake ($79): Serving up to 20 people, the five layer ice cream cake reinterprets Salt & Straw’s beloved Almond Brittle ice cream flavor, which was inspired by Tyler’s grandmother. The Tacolate ($65 for 6): The viral chocolate-covered ice cream taco (Salt & Straw × Taco Bell) is now fully giftable — cinnamon-ancho ice cream in hand-pressed waffle shells, dipped in single-origin chocolate and studded with toasted quinoa Pints Club Subscriptions (starting at $229): Three-, six-, or 12-month subscriptions featuring five-packs of best-sellers, limited-edition flavors, or plant-based options Cookbook — America’s Most Iconic Ice Creams ($28): Tyler’s newly released book, filled with never-before-seen Salt & Straw test-kitchen recipes Locations: Westfield UTC: 4575 La Jolla Village Dr #1150, San Diego, CA 92122 One Paseo: 3705 Caminito Ct Suite 0580, San Diego, CA 92130 Little Italy: 1670 India Street

A casual book signing and multi-sensory experience all in one! "Now Act! Vol. 1: Insight, Advice, and Preparation Processes from Actors, Coaches, and Casting Directors" is a unique book of personal essays about the craft and business of acting. In an industry often dominated by singular “methods” and gatekeeper perspectives, "Now Act!" offers something refreshingly different: a practical, inclusive collection of real-world insights from more than 50 working professionals across film, television, theater, and casting. One of the contributors is Giovanni Trimble, PhD. Dr Trimble authored the essay: "Navigating Intimacy in Acting: The Importance of Intimacy Coordination" and graciously offered to host this free event at their Fuzzy Glow Pop-Up Gallery with "Now Act!" Editor, Laurie Lamson. A limited number of "Now Act!" copies will be available for sale at $18 each including tax (cover price is $20.99) Fuzzy Glow Pop-Up Gallery Fuzzy Glow will only be open until the end of January, so drop by and explore how neuroaesthetics and experiential design can foster trust, emotional safety, and real connection. A perfect environment for actors! Fuzzy Glow is located in Hillcrest at University Ave. and Normal Street, behind the AWOL Bar. Check out the video of the opening: https://www.instagram.com/p/DR-JBqEjza1/ Drop by: Fuzzy Glow Pop-Up Gallery 1475 University Ave, Unit 1469 (behind AWOL Bar) San Diego, CA 92103 "Now Act!" is edited by San Diego Local: Laurie Lamson Serving as Author/Editor for multiple "Now Write!" anthologies gave Laurie the idea to create this similar collection for actors. With a filmmaking background, she has a natural rapport with actors that served her well in putting this collection together to be a grounded, accessible, useful resource for actors at different career levels.

Their experiences — of sudden financial insecurity, months of unemployment, and crippling anxiety — come as the administration seeks to restrict legal migration and boost mass deportation.