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Melissa Block talks with President Hamid Karzai of Afghanistan. Karzai is in Washington meeting with U.S. President George Bush.

President Bush was on the road Wednesday touting the $2.77 trillion budget he sent to Congress this week. The president found a receptive audience of business leaders in Manchester, N.H. But an independent survey of state voters at the end of December put Mr. Bush's approval rating at 36 percent.

Iraq's new parliament was sworn in Thursday, but the political parties deadlocked over which one will lead the next government. Renee Montagne talks to Jonathan Morrow, senior advisor with the Rule of Law Program at the U.S. Institute of Peace. He recently returned from Iraq where he's been working with the Sunni leadership on Iraq's constitution.

Polls close in Iraq after millions of people cast their ballots in a vote on whether to approve their new constitution. For the most part, the day was quiet, with only scattered reports of minor attacks. Results on the referendum won't be released until Monday.

Humanitarian groups are finding cheaper ways -- namely, filtering systems -- to clean up contaminated drinking water in developing nations. That could greatly reduce diseases caused by bacteria, viruses and parasites among the billion people worldwide who drink unsafe water.

The annual report of Reporters Without Borders finds that more journalists have been killed in Iraq since March 2003 than during the 20 years of conflict in Vietnam. Reporters have become targets in Iraq in marked contrast with reporters' experiences during the war in Vietnam.

Drugmaker Merck announces plans to slash 7,000 jobs -- 11 percent of its workforce -- and close five plants by the end of 2008. Merck's troubles include thousands of lawsuits related to its painkiller Vioxx and the impending loss of patent protection of one of its most profitable drugs, Zocor.

Several key African-American organizations gathered recently to draft a new plan in the fight against AIDS. Participants Jesse Milan (chairman of the board for the Black AIDS Institute) and Pernessa Seele (founder and CEO of The Balm in Gilead) talk with Tony Cox about the meeting.

Details from financial disclosure forms filed Wednesday by selected members of California's congressional delegation include Sen. Dianne Feinstein, Sen. Barbara Boxer, House Speaker Nancy Pelosi, Rep.

The controversial new U.S. ambassador to the United Nations has been keeping a low profile in New York. Analysts weigh in on the prospects for Bolton, a ferocious critic of the U.N., to become an effective U.S. ambassador to the United Nations.