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The FDA says esketamine, an antidepressant derived from the anesthetic and party drug ketamine, can now be prescribed on its own. It was approved in 2019 to treat severe depression.

KPBS followed a volunteer group in the annual Point-in-Time Count for Vista and San Marcos early Thursday.

Heavy snow, sleet and ice are making travel conditions treacherous across the region, stretching from Houston into the Florida panhandle.

Trump gained about 13 percentage points in San Ysidro in the most recent election compared to 2020.

Supervisor Tara Lawson-Remer spearheaded the Sustainable, Equitable and Local Food Sourcing Program. Local farmers say it's a game changer.

On his first day in the White House, President Donald Trump gave commutations and pardons to every defendant charged in the Jan. 6, 2021 attack on the U.S. Capitol. Many assaulted police.

Democrats outnumber Republicans nearly two to one in South San Diego County. But Donald Trump gained ground in the region in November, especially among Latinos and near the U.S.-Mexico border. The surprising shift suggests Democrats’ hold on the region may be slipping.

The Canadian musician played keyboard, organ and saxophone on some of group's most memorable songs.

The memo rescinds a Biden administration guideline that created "protected areas" consisting of places where "children gather, disaster or emergency relief sites, and social services establishments."

Among his day one actions, President Trump is reviving his first-term efforts to promote classical architecture for federal buildings.