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Thirteen people killed in one of the deadliest border crashes on record were among 44 people who entered the U.S. through a hole cut into Southern California's border fence with Mexico, the Border Patrol said Wednesday.

Almost a month after the Biden administration launched a program to process some asylum-seekers along the southern border, hundreds of people are now camped outside of the San Ysidro Port of Entry.

San Diego-based annual festival attracts talented photographers for virtual workshops, lectures and more with several in-person exhibitions and outdoor shows.

The San Diego Convention Center shelter for unaccompanied migrants was expected to reach its 1,450 capacity within days as another group of minors arrived Sunday, federal officials said.

As NPR celebrates 50 years on the air, host Scott Simon reflects on how the network has grown, and his time travelling the world, covering wars, famines, elections and more.

The remains of 24 pharaohs, 18 kings and four queens, were relocated to the National Museum of Egyptian Civilization on Saturday in an elaborate event designed to attract tourists to the new museum.

As the county issues cease and desist orders to organizations throughout the county for violating health orders, one county supervisor is calling for further crackdowns in the face of skyrocketing COVID-19 cases.

Grieving family members and law enforcement colleagues gathered Tuesday to bid their final farewells to a married couple who rose through the ranks of the San Diego Police Department to the post of detective together.

Elizabeth Neumann, a former assistant secretary at the Department of Homeland Security, says the Trump administration is creating the conditions for domestic extremism to flourish in the U.S.

An outdoor, changing exhibition at Lux Art Institute explores lost language, mountains, transformations and migrations.