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From the first vaccine (for smallpox) the questions have been the same. How do we transport it? Who's next to get it? Why so much hesitancy? The answers can be similar — or dramatically different.

Firefighters battled destructive wildfires north of San Francisco and in western Los Angeles neighborhoods on Monday, trying to beat back flames that forced thousands to flee their homes.

It’s Black Friday, but for locally owned stores, it’s Small Business Saturday that matters. We’ll take a look at the impact of small businesses and how the city of San Diego aims to give them a boost through its Storefront Improvement Program. Plus, San Diego City Council President Georgette Gomez is running for Congress. She sits down with KPBS to talk about her impact and legacy in District 9. And, the director for "Wally and His Lover Boys" at Diversionary's Black Box Theatre is familiar with staging a show, just not in this way before.

Police fatally shot the suspect they say rammed a car into a barrier and then lunged at officers with a knife. One officer was killed, and another was injured.

The team had stopped playing the anthem at the request of owner Mark Cuban, leading the NBA to reiterate that playing "The Star-Spangled Banner" is required under "longstanding league policy."

A man in Border Patrol custody was held for three weeks while his family and lawyers had no idea where he was or if he was even alive. KPBS has an exclusive look at how one man became lost in an overloaded immigration system. Plus, hospitals and the medical devices inside your body could be vulnerable to cyber hackers. So why are federal regulators teaming up with hackers? And, Rep. Duncan Hunter was in court Monday to see if a well-known San Diego former prosecutor could represent him at his corruption trial in January. Hunter recently fired his legal defense team.

Author Nick Neely will be signing copies of and speaking about his new book, "Alta California: From San Diego To San Francisco, A Journey on Foot to Rediscover the Golden State," Thursday at Warwick's in La Jolla.

The tension and loss that drove Marvin Gaye wasn't lost on his peers: In the same year as What's Going On, a wave of Black artists released explosive new work that put its politics front and center.

The military found that video games are more effective than traditional recruiting methods. Anyone who came to a recent Army recruitment event was able to play the new "Call of Duty" game as long as they also spoke to recruiters. Plus, Californians may be more likely to get a whiff of marijuana while walking down the street, now that the drug is fully legal in the state. One of our listeners wanted to know whether anyone's raising the alarm about secondhand pot smoke. We have an answer. And, scientists at the Scripps Institution of Oceanography found that microplastics are a million times more abundant in the ocean than previously thought. Those tiny pieces of plastics are ending up in the food chain and ultimately in humans with unknown health effects.

"Drawings show the hand of the artist," says Nicola Lorenz, Executive Director of Manhattan's Forum Gallery and curator of this exhibition. "No two artists make their marks in the same way,"