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In these prepared remarks, President-Elect Barack Obama calls himself the unlikeliest presidential candidate, and warns supporters about the enormous problems the country must now face.

The oil spill in the Gulf of Mexico is the worst spill in U.S. history. We'll examine the economic and environmental impact for California and San Diego, and whether the disaster is big enough to force a change in consumer behavior.

The debate over the United States military's partnership with Chicago Public Schools continues to intensify among parents, educators and policy experts. Pauline Lipman, a Chicago urban education expert, and Herman Badillo, a New York attorney and policy expert, analyze the ongoing debate.

What defines a concussion? And, what are the potential effects of repeated concussions on the brain? We speak to a pair of local experts about the long- and short-term effects of concussions, the latest NFL rules changes, and the challenges to identifying when a person has suffered a concussion.

This year's Nobel Prize in chemistry goes to a biologist. Roger Kornberg at Stanford University is being honored for figuring out the details of how our cells read DNA. He's not the first in his family to win a Nobel Prize. His father, Arthur Kornberg, won in 1959.

Two former Federal Reserve chairmen, a former Treasury secretary, numerous CEOs and the fabled investor Warren Buffett were among the participants in a conference Tuesday on the U.S. economy. Treasury Secretary Henry Paulson convened the session to discuss proposed regulation changes.

Americans John Mather and George Smoot (left) have won the 2006 Nobel Prize for Physics. Their work on cosmic radiation helped pinpoint the age of the universe and added weight to the big-bang theory, which holds that the universe was created 13 billion years ago in an unparalleled explosion.

Twelve states and a coalition of environmental groups sued the Bush administration in 2003 for refusing to issue regulations limiting carbon emissions from cars and power plants. Wednesday, the case reaches the Supreme Court, where justices will hear the arguments on both sides.

Host Alison St. John speaks to Professors Mary Blair-Loy and Larry Hinman about the public conference they are organizing on stem cell research. The conference will focus on the social justice issues

A recently completed pipeline pumps water from the Sahara Desert to Libyan coastal cities, which have long suffered a shortage of fresh water. It's part of a grand vision for Libya's decades-long public works project.