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James Cameron's "Avatar" may be all the current rage, but according to our critics, 2009 offered plenty of great movies. We'll talk with Beth Accomando and Scott Marks about their picks for the best and worst in film for 2009. We'll also talk about some of the big stories from the year, including a little movie by a San Diegan that scored big at the box office.

Several Republican candidates, including Rep. Clay Shaw in Florida and Sen, Conrad Burns in Montana, are running ads emphasizing how well they work with Democrats.

John Edwards, the former North Carolina senator whose 2004 presidential bid landed him on the Democratic ticket as the vice presidential nominee, once again seeks the presidency.

Despite decades of trying, scientists still haven't developed the perfect lie-detector test. Critics complain of many problems with the current polygraph test, including that it seems to measure anxiety more than honesty.

China's economic boom is creating new opportunities for multinational corporations. How do they tailor their products and their strategies to attract millions of newly minted consumers? Think ancient beauty potions and tea-flavored toothpaste.

Scientists have been searching for a malaria vaccine for decades. Now, one doctor thinks that his group is close. Dr. Fred Binka is Executive Director of the INDEPTH Network. Binka is on the verge of finding a vaccine for malaria.

Scherman's article came to the attention of Jeffrey Porro who showed it to his friend, writer and TV producer Robert Eisele. Eisele and Porro developed the idea and brought to Oprah Winfrey's company, Harpo Films. That's about the time that Denzel Washington came on board to direct and star as Tolson. The film marks his return to directing after making his directing debut in 2002 with another true story,

Although cancer researchers may have found that a cat nap could reduce the chance of having a heart attack, changing work standards in Greece are making it harder for those that have held strong to siesta traditions to catch a few midday Zzz's.

U.S.-Iranian contacts seem increasingly possible. Officially, Tehran says it will only talk with Washington once the United States has set a date for withdrawing its troops from Iraq. But behind the scenes, Iranian officials seem eager for dialogue. Iranian political leaders and analysts follow developments in the United States with rapt concentration.

To make living organisms, a bundle of genes are needed. To make a human, for instance, you would need about 23,000. Now, scientists in Japan and the Unites States report new information about the minimum number of genes you need for life. And the number is remarkably small. Scientists used to think the number was around 300, but now researchers have found a bacterium that gets by with only 182 genes. The bacteria live inside tiny insects called psyllids. They posit that the bacterium is in the evolutionary process of becoming a part of the insect.