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This year, Comic-Con celebrates its 40th anniversary with a number of milestones, including record attendance and the first-ever appearance of fan idol Peter Jackson. North America's largest pop culture convention begins Wednesday.

Why does San Diego rank so high in so many ways...and far behind in others? Our unarguable uniqueness is geographical: We are America's most populous border city. And border cities everywhere are often impacted by the decisions made in distant capitals.

San Diego's Muslim community continues to deal with stigma and misconceptions as a result of 9/11. We speak with a local imam and others within the Muslim community about what it means to be a Muslim in San Diego and how their community is affected by the long wars in the Middle East.

Today, we continue our series, Choice and Regret: A Look into the Current Abortion Debate. In part one of our series, we told you about a faction of the anti-abortion movement that believes most women regret their decision to have an abortion. Now, the other side of the story. Joanne Faryon introduces us to a San Diego woman who became pregnant when she was a teenager.

San Diego – Beginning on March 5, KPBS will broadcast V-me, a new Spanish-language television network delivering quality and educational entertainment to local Latino viewers.

"It is a raunchy, honest and refreshing comedy -- a perfect crowd pleaser for opening night," says festival programmer Michael McQuiggan. He's excited about presenting 72 films from more than ten countries. Among the foreign entries he's touting are Spain's dark comedy

For more than 20 years, a team of scientists at the National Cancer Institute has been trying to cure cancer by using a patient's own immune system. In the latest twist, they use gene therapy to enhance the immune system's ability to recognize tumors.

While reporting on the torture scandal at the U.S.-run Abu Ghraib prison in Iraq, Jackie Spinner was nearly kidnapped. Shaken by the experience, the Washington Post journalist returned to work, spending a total of nine months in Iraq.

The growing U.S.-Iran confrontation has raised fears that a conflict could threaten the oil-tanker traffic through the Strait of Hormuz. Ships from the Persian Gulf carry 40 percent of the world's crude-oil exports to global markets.

The U.N. Security Council is inching closer to a vote on imposing economic sanctions on Iran for its continuing enrichment of uranium. Iran is reacting with growing alarm to the prospect of U.N. sanctions. If adopted, the sanctions would initially be moderate.