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Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives by doing so. But nearly a third of the medicines aren't new or were repurposed many times for financial gain.

Two controversial health bills will face their final votes in the California legislature in the next two weeks.

It is fair to say that the widely held assumption that Congress gets nothing done doesn't exactly fit in 2015. Some big issues, like guns and immigration, were left on the table, though.

Authorities made arrests in seven states as they dismembered a massive illegal gambling operation that allegedly ran card games out of Rancho Santa Fe mansions, took bets from Canada to Mexico and laundered $10 million through San Diego County card clubs and Las Vegas casinos.

Many covered medicines come with high out-of-pocket costs for patients, the American Cancer Society says in a report that calls for restrictions on the tabs insurers can pass along to patients.

Many covered medicines come with high out-of-pocket costs for patients, the American Cancer Society says in a report that calls for restrictions on the tabs insurers can pass along to patients.

A plan to renovate the 100-year-old Georgia Street bridge over University Avenue in North Park moved forward Wednesday when the City Council's Infrastructure Committee voted to accept $9.5 million in federal funding for the project.

The minimum wage goes up in more than 20 states as the new year begins. President Obama wants the federal minimum to go up even more, but some affected industries say it will put a chill on hiring.

Cases before the Supreme Court on Monday test whether lawmakers in Virginia and North Carolina weighed race too heavily in redrawing congressional districts following the 2010 census.

Law enforcement officers "have been the face of oppression for far too many of our fellow citizens," Terry Cunningham said at the annual meeting of the International Association of Chiefs of Police.