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Scripps researchers say a molecular redesign of fentanyl may preserve pain relief while reducing the deadly breathing suppression that drives overdoses.

No two senior centers are alike. We visited three very different venues in L.A. to learn how they’re changing for California’s aging population.

A thrilling overtime goal by defenseman Quinn Hughes puts Team USA through to a semifinal game against Slovakia. On the other side of the bracket, Canada had its own close call, but moves on to face Finland.

The billionaire tech mogul's testimony was part of a landmark social media addiction trial in Los Angeles. The jury's verdict in the case could shape how some 1,600 other pending cases from families and school districts are resolved.

ICE officers often tell people tracking and watching them that they are breaking federal law in doing so, but legal experts say the vast majority of observers are exercising their constitutional rights.

Retiring curator Phil Unitt's final lecture explores the people and history behind the San Diego Natural History Museum's extensive bird and mammal archive.

Authorities say the bodies of eight backcountry skiers have been found and one remains missing after an avalanche near Lake Tahoe in California. Six others were found alive.

The Food and Drug Administration's about-face comes a little more than a week after the agency refused to consider the company's application to market the new kind of influenza vaccine.

When asked whether recent redistricting efforts such as those in California and Texas amount to attempts to "rig" the 2026 midterms, survey respondents most often blamed the opposing party. However, nearly 25% of members of each party also assigned responsibility to their own leaders.

Blue Line Trolley commuters were delayed Wednesday because of a tree that fell near the E Street Station in Chula Vista.