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Physician Siddhartha Mukherjee explains how cellular science could lead to breakthroughs in the treatment of cancer, HIV, Type 1 diabetes and sickle cell anemia. His new book is The Song of the Cell.

In Iran, a human rights protest movement has swept the country and authorities have cracked down on demonstrators. On Monday, the men's national team appeared to show their solidarity.

From '5 plays to see in San Diego in February' (KPBS feature) In 1955, Alice Childress wrote "Trouble in Mind" about a Black actress performing in an anti-lynching play, but that play-within-a-play was written by a white playwright and directed by a white man. Racism, rivalries, misogyny, inequality, and the fraying sense of well-meaningness are all aired out as the production gets ready — and this is how the "Trouble in Mind" plot unfolds. The Old Globe has assembled an excellent cast and crew for this story, with San Diego's Delicia Turner Sonnenberg as director, Ramona Keller as the lead and local Bibi Mama (a playwright in her own right) also in the cast. —Julia Dixon Evans, KPBS Listen to our interview on KPBS Midday Edition with director Delicia Turner Sonnenberg and actor Bibi Mama, and read the full feature here. From the theater: The Old Globe is proud to present "Trouble in Mind", a thrilling new production of a too-often neglected American classic. About the play —New York, 1955. A leading Black actress and a multiracial cast rehearse a challenging new Broadway play set in the South. Backstage rivalries and showbiz egos cause excitement of their own, but artistic differences between the cast and the White director soon bubble to the surface, revealing the truths that American drama covers over and the ways in which even well-meaning people can harm others under the guise of helping. Contains strong language. The New York Times recently called Alice Childress’s groundbreaking Trouble in Mind “a rich, unsettling play that lingers in one’s memory long after its conclusion.” "Trouble in Mind" will be showing at The Old Globe from Saturday, February 5 through Sunday, March 13. Open Caption Performance on Saturday, February 26, 2022 at p.m. Click here for ticket and subscription information. For more information, please visit www.theoldglobe.org or call (619) 234-5623.

This New Year marks a fresh start, and you can begin by advocating for a local foster youth today! Our CASA volunteers ensure our youth have the support they need to thrive this year, while also acting as a caring consistent presence during this difficult time. To reach our goal, we need your help. Consider giving 10-15 hours a month, and you can make sure a foster youth enters the New Year on the right foot. Help us provide a trained advocate for every child who needs one – visit our website to sign up for a volunteer information session! Date | Saturday, January 8 at 10 a.m. Location | Online via Zoom Register here! Our Volunteer Information Sessions are free and open to the public. For more information, please visit www.speakupnow.org or call (858) 569-2019.

Two former deputy public defenders say in lawsuits that the office retaliated against them after they reported a senior supervisor for using racist terminology. Their trials are set to begin in the coming months.

UPDATE: The New Play Festival has been rescheduled for April 1-3, 2022 New Village Arts, North County's cultural hub, is hosting its annual Final Draft New Play Festival which solicits emerging playwrights to submit a 10-minute, one act full length play that will be performed during the festival in January 2022. Special encouragement is given to underestimated and underrepresented community members in order to represent all artist voices in the community. Performances include 10 never before seen plays written by talented local playwrights, as well as delicious craft beers. If you'd like to partake in the storytelling, grab a pint and join the artists panel where community artists and leaders share what changes they'd like to see in the San Diego art scene, try monologue writing at the playwrighting workshop, or even take to the stage at the kickoff party open mic night. Date | From Friday, April 1 through Sunday, April 3, 2022 Location | New Village Arts Get tickets here! Select the play or workshop you would like to attend. For more information regarding submissions, click here. Cheers to another year of brilliant local artists! For more informtion, please visit newvillagearts.org/final-draft-new-play-festival-2 or call (760) 433-3245.

On the first Monday of every month, enjoy all the Fleet Science Center has to offer! Seniors 65 and better enjoy discounted admission of $10, a show in the Heikoff Giant Dome Theater and the opportunity to attend an engaging lecture about exciting scientific topics. Date | First Monday of every month Location | The Fleet Science Center Get tickets here! Adult admission (ages 13-64): $21.95 Child admission (ages 3-12): $18.95 Senior admission(ages 65+): $19.95, $10 on Senior Mondays For more information, please visit fleetscience.org or call (619) 238-1233.

Featuring members of the artistic group, California Fibers, this exhibition focuses on the interplay between concept and material. How artists conceive and create ideas are inextricably linked, with concept sometimes guiding the material choice, while at other times the available materials inform the concept of the piece. These artists work in the in-between, using the material and immaterial to communicate ideas and concepts. Date | Available from January 15 through March 6. Check museum's hours. Location | California Center for the Arts, Escondido Get tickets here! General (standard) admission: $12 Student and Senior admission: $6 For more information, please visit artcenter.org or call (760) 839-4138.

Experience the magic and charm of winter like never before when you join us for Winter Festival on Friday, January 7 from 5-9 p.m. and Saturday, January 8 from 3:30-8:30 p.m. at Poway Community Park! Whether it’s building a snowman, sledding down the snow hill, roasting marshmallows by the campfire, making silly faces in the photo booth, or taking a spin around the synthetic skate rink, there is bound to be something for everyone! A variety of old favorites and exciting new specialty and food vendors will be on-site. All visitors are encouraged to come curious and hungry! Free shuttles to and from the event will be available from two nearby locations: Poway City Hall parking lot, located at 13325 Civic Center Drive; and the Boys and Girls Club parking lot at 12988 Bowron Road. Entrance, ice skating, skate rentals, snow hill, sled use, crafts, bounce house, winter games, snow play areas, and photo booth are free. Food and specialty vendors, including pony rides, do charge a fee. ATM machines will not be available at the event; as some vendors are cash only, visitors should plan accordingly.

“The Grand State Reopening” kicked off yesterday and much of San Diego rejoiced. But public health officials are warning that the pandemic still isn’t over. Meanwhile, a grassroots organization called “Let Oceanside Vote,” is collecting signatures to recall Kori Jensen, the Council member for District 1 in Oceanside. Plus, can the movie ‘In The Heights’ change Hollywood’s racial landscape?