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Republican Rep. Darrell Issa praised the ruling, calling it a historic win for the Trump administration and the rule of law.

The decades-old radical troupe Bread and Puppet, famed for its protest art including giant puppets, is touring again — mixing circus, politics and bread in a sharply polarized moment.

Lecture title: Regenerative medicine for the treatment of MS: Enhancing repair to prevent progression Front Row lecture with Luke Lairson, PhD Description: Multiple sclerosis (MS) is a debilitating autoimmune disease that disrupts the central nervous system, causing symptoms like muscle weakness, cognitive challenges and a gradual loss of function that current treatments cannot fully repair. MS arises when the immune system attacks the myelin sheath, the protective layer insulating neurons. Scripps Research chemistry professor Luke Lairson will discuss his research on the body’s natural repair pathways—specifically those that activate endogenous stem cells to restore myelin. His work aims to develop therapies that complement existing therapeutic approaches and halt MS progression. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its eighth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. Join us—in the front row. Scripps Research on Facebook / Instagram / TikTok

Experience the Fleet Science Center like never before—exclusively for ages 18+! With the museum all to yourselves, you can explore 100+ interactive exhibits, unleash your creativity in Studio X, our hands-on makerspace, and experience our latest exhibitions. Reconnect with your sense of wonder as you engage with the Fleet’s signature hands-on, minds-on science experiences. Whether you’re bringing friends or flying solo, Fleet After Dark is your chance to explore, play, and discover in a whole new way. Let's Play a Game: Join the Let's Play a Game foundation at Fleet After Dark where they're making board games accessible to everyone! Join a table, meet new folks and build your community while tapping into the nostalgia and adventure of analog gameplay. Fleet After Dark happens every fourth Thursday (excluding, April, November and December). Fleet Science Center on Facebook / Instagram

Despite experts saying that famine has begun in Gaza, Israel is threatening more curbs on aid deliveries. Aid groups say extra restrictions will make the starvation crisis worse.

Republicans are "nervous" about President Trump's tariffs raising prices, says Democratic Sen. Tim Kaine of Virginia. He plans to force a vote in the Senate on them soon.

City Heights residents are pushing back against budget cuts to rec centers and libraries. Then, a new report says Medi-Cal patients are hospitalized for preventable conditions twice as much as Californians with private insurance. And hear the latest on the Marine Corps’ controversial contract with an Oceanside-based credit union. Plus, Governor Gavin Newsom released $3 billion for behavioral health and housing — we’ll tell you what San Diego organizations will benefit. Finally, we look at how automated bots are scooping up the best tee times at city golf courses.

San Diegans will have multiple opportunities to honor those who lost their lives in service to the nation this Memorial Day weekend.

Noah Wyle, Owen Cooper, Seth Rogen, Jean Smart, Tramell Tillman, Jeff Hiller and Stephen Colbert are all taking home awards tonight. Check out our list of winners.

The Justice Department announced charges in what officials describe as the largest health care fraud bust in DOJ history.