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For most people, change can be uncomfortable. Even unsettling. But if you can move past the discomfort, it’s often in those awkward moments, that you will grow and evolve, as a person. In this spirited discussion, we’ll talk with Melissa and Michael Harlow who did a major life pivot in their 50’s. How did they muster the courage? And more importantly, what steps did they take to ensure they could handle it… physically, mentally, and financially? Presenters: Michael and Melissa Harlow both enjoyed successful corporate careers, and several years ago decided to quit their jobs and sell everything they own to lead a simpler life and travel the world. Moderator: Darlynne Reyes Menkin is an award-winning journalist who worked in several different television markets including Philadelphia, Las Vegas, and Washington, D.C. before settling in San Diego. Darlynne’s journey from TV news anchor to running a successful local team-building company is a unique story filled with lots of ups and downs. She was recently named “Entrepreneur of the Year” by Smart Meetings, and a “Women of Influence” by the San Diego Business Journal. Visit: Living Your Best Life: a Health and Wellness Speaker Series Grossmont Healthcare District on Instagram and Facebook

A new study suggests a link between high levels of fluoride and lowered IQ. It's heating up arguments over fluoridating drinking water, which dentists say is critical for protecting teeth.

Lecture title: Delivering medicines for a global population - Front Row lecture with Arnab Chatterjee, PhD Description: Infectious diseases like tuberculosis and malaria pose an ever-increasing risk to communities around the world. Meanwhile, a lack of investment, long treatment protocols and drug resistance have stymied innovation in this area. In this free Front Row lecture, vice president of medicinal chemistry Arnab Chatterjee will discuss how the Calibr-Skaggs Institute of Innovative Medicines—the drug discovery and development arm of Scripps Research—is using innovative new approaches and technologies to overcome these historic barriers. His work at the Calibr-Skaggs Institute is helping accelerate the delivery of safe, effective and accessible medicines to countries spanning the globe. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its seventh season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. In 2024 we celebrate a century of turning vision into pioneering impact. Reserve your seat today and learn how our scientists remain at the forefront of advancing the future of science and medicine. We hope you’ll join us—in the front row—for the next century of Science Changing Life. Visit: Delivering Medicines for a Global Population Scripps Research on Instagram and Facebook

The Los Angeles County Medical Examiner said that it has received notification of 10 fire-related deaths as firefighters battle multiple blazes for a third consecutive night.

Vantage Theatre Presents A World Premiere Production "Best Laid Plans" by Robert Salerno Inspired by a true story, a brilliant young architect has surgery for a brain tumor and wakes up unexpectedly blind. Alone, lost and despondent, he cannot envision a path back to life, much less architecture...Then Beethoven shows up! Featuring Blake Stadnik, the Blind Actor from NBC's hit series "This Is Us" Directed by Sam Woodhouse The Show Runs: Aug. 29-Sept. 22, 2024 Thursday Aug. 29 (ONE Preview) 7:30 - 9:30 p.m. Friday + Saturday at 7:30 p.m. Saturday + Sunday at 3 p.m. Located at: Tenth Avenue Arts Center 930 10th Ave, San Diego, California Visit: https://theatrevantage.ticketspice.com/best-laid-plans Made possible in part by a grant from the Prebys Foundation and The California Arts Council and with the support of the Sofia Hotel

The winter storm could bring heavy snow and freezing rain, making for dangerous conditions. Some states are used to such weather and have advice for how to prepare.

The New York Stock Exchange and the Nasdaq will both observe Thursday's national day of mourning in a Wall Street tradition dating back to 1865.

Research shows including students with and without disabilities in the same classroom can benefit everyone. Two students with Down syndrome show what can be gained when that happens.

The service, which lasted roughly two hours, was packed with heartfelt and vivid remembrances that recalled both a powerful president and politician as well as a thoughtful and giving man of faith.

"We're in a unique situation in Canadian politics," Shachi Kurl, president of the Angus Reid Institute, tells NPR. Voters need to replace a lame-duck leader — and cope with threats from Trump.