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Researchers warn betting on clinical trials could incentivize insider trading and interfere with drug development. But Kalshi and Polymarket say they provide valuable information to patients.

First, we’ll tell you some of the contributing factors around why 2025 was the deadliest year ever recorded for U.S. Immigration and Customs Enforcement Detention Centers. Then, we’ll tell you why more and more flights coming from San Diego’s military airports are deportation flights. And, we’ll tell you about a new legislature that looks to build more affordable housing in our cities’ urban centers. Also, uncomfortable conversations around death are moving to more social settings like a bar. And, International Dark Sky Week is here! We’ll tell you about some of the stargazing events happening across San Diego County this week.

Hundreds of thousands of civilians in el-Obeid are being battered by relentless drone strikes and face critical water shortages and a worsening cholera outbreak, while women and girls are reporting high rates of sexual violence.

Deaths and close calls while fighting wildfires have strained an already on-edge workforce. They've also raised questions about policies and priorities amid an intense wildfire season.

Plus, if you know what "TMZ" stands for, you'll get at least on question right this week!

Over the last decade, reality TV mogul Andy Cohen has been spotted dancing at concerts for Dead & Company. But his ties to the Grateful Dead go much farther than that.

Polls show most Americans think young adults today have it harder financially than past generations. A majority of parents help their grown children with expenses, even if it hurts their own finances.

The motive is still under investigation, though there were reports he had been stressed in connection with school.

Judge Bryan Biedscheid said in a ruling late Thursday that the bulk of the money will be used for treatment services for young people.

Get ready for a night of nonstop laughs at Last Laugh Friday at The Bornemann, hosted by actor and comedian Mark Christopher Lawrence. This stacked lineup brings together nationally touring comics and standout talent for an evening of smart, high-energy comedy. Headlining the night is Frances Dilorinzo, the viral comedy sensation behind “Homemade Implants” and “Phone Talk,” with millions of views online and appearances on NBC, ABC, CBS, Comedy Central, TLC, Nickelodeon, and more. Frances delivers a fearless mix of intelligent, silly, and physical comedy that pulls audiences into her wildly relatable world. Joining the lineup is Carlos Kotkin, an award-winning comedian, writer, and former ring announcer for the World Famous Iceoplex. Known for his quick wit and unpredictable storytelling, Kotkin has written for major television productions and performed comedy nationwide, blending sharp observations with offbeat charm. Opening the show is Chris Angell, a nationally touring comedian and former radio personality whose laid-back delivery and relatable humor have made him a favorite on comedy stages across the country. With stories drawn from everyday life, family, and modern absurdities, Angell brings an effortless style that connects instantly with audiences. Three great comics. One unforgettable night. Come early, grab a drink, and get ready for the non-stop laughter! While we welcome all ages, discretion is advised.