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Lecture title: Close encounters: Designing drugs that recruit the cell’s own machinery to fight cancer and beyond – Front Row lecture with Michael Erb, PhD Description: Some of the most devastating diseases are driven by proteins that cannot be targeted with conventional drugs. Scientists are now discovering ways to control disease by recruiting the cell’s own machinery to tackle this challenge. In this free Front Row lecture, Associate Professor Michael Erb will take the audience inside the cell to explain how his team is developing “proximity” drugs. Erb’s innovation has implications to change how scientists and cells join forces to fight against breast, prostate and blood cancers. Join us to learn how proximity drugs can eliminate proteins, rewire essential cellular pathways, and enable researchers to target previously “undruggable” proteins. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its ninth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Instagram and Facebook

Renowned vocalist Mel Collins returns with her quartet for "Loving the Lyrics," an elegant evening celebrating the timeless songs of the mid-20th century. Featuring music made famous by artists like Ella Fitzgerald, Nancy Wilson, and Rosemary Clooney, the concert highlights the brilliance of legendary songwriters including Rodgers & Hart, Cole Porter, and Dorothy Fields. Mel Collins on Instagram

Join local rescue groups to meet 100+ adoptable dogs and cats.. Connect with local organizations that are making a difference and learn about volunteer opportunities, fostering and other ways to help homeless animals in San Diego. This is a rain or shine event. Viridian Productions Sustainable events that cultivate community and inspire healthy living, featuring a rotating lineup of diverse vendors offering the most eco-friendly food, products, and services in Southern California. Shaping a greener future through connection and local impact. Learn more: https://www.viridianproductions.com Viridian Productions on Facebook / Instagram

Come escape the ordinary with this modern-day Vaudeville act at the historic Sunshine Brooks Theater (217 N. Coast Highway, Oceanside, CA)! A night of fun-filled jazz on the mythical Moulin Rouge stage. Our international ALL STAR cast features Luca Pino, Eva Mikhailovna (and the Pepper Moons), Idun Carling, Rosemary Watson, Billy Galewood and Dexter Berrogain. Oceanside Theatre Company on Facebook / Instagram

To conclude our thrilling Solo Series, celebrated harpsichordist and organist Benjamin Alard returns for an artist residency at All Souls, featuring two recitals over two days. Highlights include the Italian Concerto on harpsichord on Friday evening and the iconic Toccata and Fugue in D minor on the organ on Sunday. Don’t miss these two evenings of “superbly and sympathetically played” (San Diego Union-Tribune) music. San Diego Early Music Society on Facebook / Instagram

The annual San Diego Early Music Sing-Along is back! Join us for a joyful evening of singing favorites from the early music vocal repertoire. Led by Dan Ratelle, this event is open to singers of all levels. This is a FREE event! Music and refreshments will be provided. Register now on our website, under our outreach tab! San Diego Early Music Society on Facebook / Instagram

Three-time Grammy® Award winner and global icon Sarah McLachlan announces the 2026 extension of her "Better Broken Tour," produced by Live Nation, in support of her critically acclaimed tenth studio album of the same name, released September 19, 2025 via Concord Records. The summer run will kick off in Franklin, TN at FirstBank Amphitheater and travel across the U.S. with stops in Atlanta, Philadelphia, Boston, Chicago, San Diego, Bend, and more, before concluding with two nights on August 8 and 9 in Woodinville, WA at Chateau Ste Michelle Winery. The tour will also feature performances at several iconic venues, including Forest Hills Stadium in Forest Hills, NY, Red Rocks Amphitheatre in Morrison, CO, and two nights at the Greek Theatre in Los Angeles, CA. Special guest Allison Russell will join on all upcoming dates. Montreal-born and Nashville-based Russell is a Grammy, Juno Americana, Socan & Folk Awards-winning & Polaris Prize short-listed artist, actor, author, songwriter, producer, human rights advocate survivor and mother. She is the co-founder of Once and Future Sounds and Love Rising. Her debut solo album Outside Child was released in 2021, followed by The Returner in 2023 via Concord/Fantasy Records. The newly announced dates follow McLachlan’s sold-out fall run, which spanned nine major cities across the U.S., including Washington, DC, Philadelphia, New York City, Boston, Chicago, Minneapolis, Seattle, San Francisco, and Los Angeles. Please note: This is a rental event of The Rady Shell at Jacobs Park, presented by Live Nation. The San Diego Symphony Orchestra does not appear on this concert. Sarah McLachlan on Facebook / Instagram

Join us for a fun and impactful pickleball fundraiser benefiting the Boys & Girls Club of South County in Imperial Beach! Your participation in the open play event helps support programs that provide youth with a safe, supportive environment and opportunities to thrive. Whether you're a seasoned player or brand new to pickleball, come enjoy an afternoon of games, community building and giving back. If you're unable to attend, you're still welcome to participate in the silent auction. Please register for the event by April 20, 2026.

The Friendly Feast 420 Bake Sale features top-tier treats created by some of San Diego’s most creative pastry chefs. Guests can enjoy a curated box of baked goods designed to satisfy sweet and savory cravings, including a "Wake and Bake" breakfast scone, ube cheesecake doughnut, Snickers brownie cheesecake bar, and more. VIP boxes on sale now. General sale starts Thursday, April 9. Indulge for a good cause! 100% of proceeds from this community fundraising event support the Friendly Feast scholarship fund, which helps aspiring pastry chefs and professional bakers achieve their educational goals. Friendly Feast on Facebook / Instagram

Dr. Will Tuttle, author of international best seller, "The World Peace Diet," published in 19 languages, has lectured and performed in over 50 countries. This event will be lecture, piano concert, and incredible animal artwork. Madeline Tuttle, animal paintings, artist from Switzerland, flautist, Waldorf teacher, organic gardener, vegan chef. You will gain the tools to understand the power of food to heal us not just physically, but also culturally and psychologically, and how to more effectively bring this understanding to your friends and family. Www.worldpeacediet.com for more info