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The vaccine, developed in a partnership between the pharmaceutical giant and a German biotech company, began trials on Monday with 360 volunteer subjects.

The County Board of Supervisors voted unanimously Wednesday to rescind the Climate Action Plan it adopted in February 2018 and move forward in creating a replacement.

The Carlsbad City Council has approved a $5 million economic revitalization package to help businesses affected by the COVID-19 pandemic, and will accept applications for the relief Wednesday through May 25.

Enticed by what young adults had to share about the pandemic, historian Alexandra Zapruder set out to document history through an online gallery called Dispatches from Quarantine.

In a wide-ranging interview, House Speaker Nancy Pelosi also said she opposes the efforts of leading 2020 Democratic presidential candidates to enact a government-run health care system.

This was meant to be the year we answered a big question about the deadly opioid epidemic: Will drug companies that make and sell prescription pain medications be held liable? That clarity never came.

California's roads may soon be made of plastic, an idea that was born and is being developed in San Diego.

The number of laid-off workers seeking unemployment benefits remained stuck at 1.3 million last week, an historically high level that indicates many companies are still cutting jobs as the viral outbreak intensifies.

U.S. Geological Survey confirms the shaking and boom heard throughout some parts of San Diego County wasn’t an earthquake but maybe a sonic boom.

The Dow Jones Industrial Average and other major stock indexes plunged Tuesday after Trump administration officials accused Beijing of reneging on commitments it had already made in the talks.