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Cook, who has led Apple since 2011, spoke with NPR's Steve Inskeep in a wide-ranging interview on Monday as the company kicked off its annual Worldwide Developers Conference.

A cool storm doused the San Diego area with intermittent downpours Tuesday and buffeted the region with high winds, ending a lingering spate of summer-like heat and humidity.

San Diego Mayor Kevin Faulconer was widely thought to be coasting to re-election on June 7. But now with two high-profile challengers — former Assemblywoman Lori Saldaña and former City Councilman Ed Harris — Faulconer has been forced to defend his record in office.

Author Maia Szalavitz argues that it's impossible to destigmatize addiction while also rendering it the only diagnosis in medicine for which the treatment is explicitly moral.

Privately funded scientists made a virus related to smallpox from scratch, hoping their version might lead to a better smallpox vaccine. But critics question the need — and worry about repercussions.

A bill designed to increase Medi-Cal patients’ access to interpreters is moving through the state Legislature.

School's principal gives credit to ex-Superintendent Alan Bersin

Illumina Inc. reported Tuesday that it's teaming up with cattlemen in Ireland to improve the breeding of livestock.

The city and county of San Diego would pay $350 million combined under a financing proposal unveiled Monday for a new football stadium in Mission Valley, or about one-third of the total construction cost.

As President Trump approaches his 100th day in office, White House correspondent Maggie Haberman of The New York Times says "the magnitude of the job is sinking in for him."