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Scripps researchers say a molecular redesign of fentanyl may preserve pain relief while reducing the deadly breathing suppression that drives overdoses.
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San Diego's indie-rock project Topeka Clementine blends storytelling, activism and sing-along energy into music that feels urgent and alive. Hear a special performance from KPBS' Sundrenched Sounds live music series and a post-show interview about going viral, constant touring and new work shaped by grief and hope.
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Matt Hoffman/KPBSBlue Line Trolley commuters were delayed Wednesday because of a tree that fell near the E Street Station in Chula Vista. -
Ben Lacy/KPBSThousands of San Diego Gas & Electric customers were without power Wednesday following multiple outages reported across the South Bay. -
Rich Predroncelli / AP / Evan Vucci / APWhen asked whether recent redistricting efforts such as those in California and Texas amount to attempts to "rig" the 2026 midterms, survey respondents most often blamed the opposing party. However, nearly 25% of members of each party also assigned responsibility to their own leaders. -
Charlotte Radulovich/KPBSThe County Administration Building in downtown San Diego will lower its flags to half-staff and illuminate in rainbow colors this evening in honor of the late Rev. Jesse Jackson, it was announced Wednesday.
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Slacker performs a full pop-up concert on the KPBS patio. -
KPBS Midday EditionLunar New Year celebrations are underway in San Diego and across the globe as more than one million people usher in the Year of the Horse. -
KPBS Midday EditionFor our Black History Month profile series, we sit down with local leader Kyra Greene to talk about her fight for working class San Diegans. Then, skateboarding photographer Atiba Jefferson looks back at his career.
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San Diego has not seen the surges in deportation forces like in Minneapolis and a few other cities. But federal agents have arrested thousands of San Diegans. -
The departure of Vaughn Maurice, who led the San Diego County Department of Animal Services, came after the county cut ties with his second in command two weeks ago.
How Trump’s mass deportation agenda is playing out in San Diego
This El Cajon museum takes visitors back to the frontier days of the Old West
How a new law could help one local family trapped in parking citation debt
Environmental costs spark a movement against massive Imperial Valley data center
The developers behind plans to build a massive data center in Imperial County
The plan to build massive data center in Imperial County — without environmental review
From naval training center to arts hub: Arts District Liberty Station marks 25 years
How a SANDAG database might be aiding Trump’s deportation campaign
Imperial Beach residents mourn Gary Gates and question why deputies shot him
Immigration enforcement changes the holidays for undocumented families in San Diego
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First, State Senator Steve Padilla is calling for a pause to a data center project in Imperial County. Next, scientists say they’ve discovered a way to redesign Fentanyl and lessen the potential risk of an overdose. Also, we tell you about a new fundraising and awareness campaign recently launched in the county. Lastly, a curator at the San Diego Natural History Museum is calling it a career. -
As the city of San Marcos launches its effort to become a "Blue Zone" community, we hear from a local physician about what the "Blue Zone" approach entails and what it could mean for community health at large.
- How does the partial government shutdown impact San Diego?
- DHS Secretary Kristi Noem visits Otay Mesa, says border is secure
- Kristi Noem to visit border near San Diego as polls show declining support for Trump policies
- Overtime pay and night vision binoculars: UC San Diego is among agencies helping patrol border
