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Lecture title: The sweet side of drug discovery: How sugars can help shape the future of medicines - Front Row lecture with Yuzhong Liu, PhD Description: Some of the most powerful medicines we use today come from natural products, which are specialized molecules that plants and microbes have evolved over millions of years. Sugars play a key role in these compounds—determining how the molecule behaves, where it travels in the body and how strongly it activates the immune system. In this free Front Row lecture, Scripps Research chemist Yuzhong Liu will demonstrate how her lab uses synthetic biology to decode the role of sugars in medicine—helping scientists build next-generation vaccine adjuvants, cancer therapies and safer treatments. ABOUT SCRIPPS RESEARCH Scripps Research is an independent, nonprofit biomedical institute based in La Jolla, California, and ranked one of the most influential in the world for its impact on innovation. The Front Row lecture series, now in its ninth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Join us—in the front row. Reserve your seat! Settle into our auditorium for an inspirational, in-person experience, or attend virtually with thousands of people from around the world. Scripps Research on Instagram and Facebook

Studio ACE Gallery invites artists of all levels and backgrounds to submit work now through Sunday, January 25, 2026, for "Common Threads: The Fabric of Our Community," a juried exhibition celebrating the rich, expressive world of textiles and fiber arts. Call for Artists Closes: Sunday, January 25, 2026 To Apply: https://artist.callforentry.org/festivals_unique_info.php?ID=16630 Textiles—among the oldest and most universal artistic mediums—carry stories in every stitch. Woven, sewn, dyed, layered, felted, quilted, knotted, or repurposed, fiber-based materials offer a tactile language that speaks to memory, identity, resilience, and cultural tradition. From the intimate textures of handwork to bold contemporary experiments with fabric, thread, and mixed media, textile art reminds us that creativity is something we all touch, wear, and share. This exhibition seeks works that explore connection—connections between people, cultures, materials, and ideas. We welcome pieces that honor traditional craft, push the boundaries of fiber as a modern art form, or reimagine textiles in unexpected ways. Whether your work is deeply personal, abstract, conceptual, or rooted in community stories, we want to hear your voice. Join us as we bring together the diverse perspectives that make up the fabric of our community. "Common Threads: The Fabric of Our Community" will be on view at ACE Gallery (inside Studio ACE) from Saturday, February 21, through Friday, March 27, 2026, with an opening reception celebration taking place on Saturday, February 21, from 5-7 p.m. Studio ACE on Facebook / Instagram

SD Baroque again joins forces with up-and-coming LA-based soprano Addy Sterrett for a program centered on Italian vocal chamber works from the early 18th century, including Alessandro Scarlatti’s exquisite "L’Olimpia" and Handel’s "Crudel tiranno amor" HWV 97. Admission is free. San Diego Baroque on Facebook / Instagram

After threatening to sever ties with the organization formerly known as the Boy Scouts, Defense Secretary Hegseth announced a 6-month reprieve

The Defense Department has been feuding with Anthropic over military uses of its artificial intelligence tools. At stake are hundreds of millions of dollars in contracts and access to some of the most advanced AI on the planet.

In his annual budget, President Trump is asking Congress to boost defense spending to $1.5 trillion, the largest such request in decades.

Experience a Grand Feast on Christmas Eve with an opulent four-course tasting menu at Amaya. Reservations available on Opentable. Fairmont Grand Del Mar on Facebook / Instagram

Organization Systems International (OSI), a San Diego-based company specializing in science-based leadership and management talent solutions, will host a two-day, in-person business simulation experience January 21-22, 2026, at the UCSD Rady School of Management in San Diego. The $2 Billion Challenge Leadership Experience will give participants the opportunity to take control of Paper Nation—a global pulp and paper manufacturer—and compete to lead the company through six simulated years of growth. Emerging and mid-level leaders, HR and Learning & Development professionals, C-suite leaders seeking a fresh perspective, and multi-generational teams looking to enhance collaboration are invited to join us for the opportunity to experience: - High-stakes decision-making without the real-world risk - Strategic thinking as you navigate a shifting marketplace - Financial gameplay using P&Ls, balance sheets and ROI - Rapid rounds of action plus feedback The event will feature two engaging days of fun and learning led by Bruce Griffiths, OSI President, and Rick Morales, Senior Consultant. For registration details and more information visit https://orgsysint.com/2-billion-challenge-a-leadership-experience/.

Come join us for a jolly good time at our Merry Grinchmas Paint & Sip on The Deck! Get into the holiday spirit at Santee Lakes as we sip and unleash our inner artists in this guided step by step paint session. Whether you’re a beginner or a seasoned painter, this event is perfect for everyone – family & friends. Let’s spread some holiday cheer together while creating beautiful artwork on the deck. Don’t miss out on this fun and creative experience! Drinks & food available for purchase – table service & promotional drinks available! Visit: 'Merry Grinchmas' Paint and Sip Santee Lakes on Instagram and Facebook

The stadium-filling singer-songwriter's fourth album is full of finely detailed songs that expand his sound without sacrificing subtlety.